Nbd-colcemid structure

Nbd-colcemid

TL;DR: Nbd-colcemid (CAS 108964-31-4) is a chemical compound with molecular formula C27H26N4O8 and molecular weight 534.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(7S)-1,2,3,10-tetramethoxy-7-[methyl-(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]-6,7-dihydro-5H-benzo[a]heptalen-9-one

Also Known As: Nbd-colcemid, Nbd-demecolcin, N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)colcemid, (7S)-1,2,3,10-tetramethoxy-7-[methyl-(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]-6,7-dihydro-5H-benzo[a]heptalen-9-one, (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methyl(7-nitro-4-benzofurazanyl)amino)benzo(a)heptalen-9(5H)-one

CAS: 108964-31-4
Molecular Formula C27H26N4O8
Molecular Weight 534.18 g/mol
LogP 2.7
Topological Polar Surface Area 142.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 11
Rotatable Bonds 6
Exact Mass 534.17505
Heavy Atoms 39
Complexity 1040.0

Chemical Identifiers

CAS Number 108964-31-4
SMILES CN([C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC)C4=CC=C(C5=NON=C45)[N+](=O)[O-]
InChIKey DQARLXAFVVPTDP-KRWDZBQOSA-N

Product Overview

Nbd-colcemid (CAS 108964-31-4), with molecular formula C27H26N4O8 and molecular weight 534.18 g/mol. IUPAC: (7S)-1,2,3,10-tetramethoxy-7-[methyl-(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]-6,7-dihydro-5H-benzo[a]heptalen-9-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Nbd-colcemid

XLogP
2.7
TPSA (Topological Polar Surface Area)
142.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
11
Rotatable Bonds
6
Heavy Atoms
39
Complexity
1040.0
Exact Mass
534.17505
Monoisotopic Mass
534.17505
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nbd-colcemid

The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nbd-colcemid. The TPSA of 142.0 Ų indicates high polarity, suggesting Nbd-colcemid may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nbd-colcemid has 0 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nbd-colcemid?

The CAS number of Nbd-colcemid is 108964-31-4.

What is the molecular formula of Nbd-colcemid?

The molecular formula of Nbd-colcemid is C27H26N4O8.

What is the molecular weight of Nbd-colcemid?

The molecular weight of Nbd-colcemid is 534.18 g/mol.

Where can I buy Nbd-colcemid?

You can request a quote for Nbd-colcemid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nbd-colcemid?

Yes, KEHONG BIO provides custom synthesis services for Nbd-colcemid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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