Lorpiprazole
TL;DR: Lorpiprazole (CAS 108785-69-9) is a chemical compound with molecular formula C21H26F3N5 and molecular weight 405.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,8S)-5-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-3,4,6-triazatricyclo[6.3.0.02,6]undeca-2,4-diene
Also Known As: Lorpiprazole, lorpiprazol, lorpiprazolum, Lorpiprazole [INN], (+-)-cis-5,5a,6,7,8,8a-Hexahydro-3-(2-(4-(alpha,alpha,alpha-trifluoro-m-tolyl)-1-piperazinyl)ethyl)cyclopenta(3,4)pyrrolo(2,1-c)-s-triazole
| Molecular Formula | C21H26F3N5 |
|---|---|
| Molecular Weight | 405.21 g/mol |
| LogP | 3.5589 |
| Topological Polar Surface Area | 37.19 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 405.21402 |
| Heavy Atoms | 29 |
| Complexity | 869.4418 |
Chemical Identifiers
| CAS Number | 108785-69-9 |
|---|---|
| SMILES | C1C[C@@H]2CN3C(=NN=C3[C@@H]2C1)CCN4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F |
Product Overview
Lorpiprazole (CAS 108785-69-9), with molecular formula C21H26F3N5 and molecular weight 405.21 g/mol. IUPAC: (1R,8S)-5-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-3,4,6-triazatricyclo[6.3.0.02,6]undeca-2,4-diene.
Chemical Property Profile of Lorpiprazole
Property Insights of Lorpiprazole
The XLogP value of 3.5589 indicates that Lorpiprazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.19 Ų, Lorpiprazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lorpiprazole has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lorpiprazole?
The CAS number of Lorpiprazole is 108785-69-9.
What is the molecular formula of Lorpiprazole?
The molecular formula of Lorpiprazole is C21H26F3N5.
What is the molecular weight of Lorpiprazole?
The molecular weight of Lorpiprazole is 405.21 g/mol.
Where can I buy Lorpiprazole?
You can request a quote for Lorpiprazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lorpiprazole?
Yes, KEHONG BIO provides custom synthesis services for Lorpiprazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.