Pregnenolone-naltrexone azine structure

Pregnenolone-naltrexone azine

TL;DR: Pregnenolone-naltrexone azine (CAS 108743-74-4) is a chemical compound with molecular formula C41H55N3O4 and molecular weight 653.42 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(7E,7aS)-3-(cyclopropylmethyl)-7-[(E)-1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethylidenehydrazinylidene]-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol

Also Known As: Pregnenolone-naltrexone azine, PH-NX, Naltrexone-pregnenolone mixed azine, Pregn-5-en-20-one, 3-hydroxy-, ((5alpha,6E)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-ylidene)hydrazone, (3beta,20E)-, (7E,7aS)-3-(cyclopropylmethyl)-7-[(E)-1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethylidenehydrazinylidene]-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoq

CAS: 108743-74-4
Molecular Formula C41H55N3O4
Molecular Weight 653.42 g/mol
LogP 6.7131
Topological Polar Surface Area 97.88 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 7
Rotatable Bonds 4
Exact Mass 653.41925
Heavy Atoms 48
Complexity 1647.5137

Chemical Identifiers

CAS Number 108743-74-4
SMILES C/C(=N\N=C\1/CCC2(C3CC4=C5C2([C@@H]1OC5=C(C=C4)O)CCN3CC6CC6)O)/[C@H]7CC[C@@H]8[C@@]7(CC[C@H]9[C@H]8CC=C1[C@@]9(CC[C@@H](C1)O)C)C

Product Overview

Pregnenolone-naltrexone azine (CAS 108743-74-4), with molecular formula C41H55N3O4 and molecular weight 653.42 g/mol. IUPAC: (7E,7aS)-3-(cyclopropylmethyl)-7-[(E)-1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethylidenehydrazinylidene]-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pregnenolone-naltrexone azine

XLogP
6.7131
TPSA (Topological Polar Surface Area)
97.88
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
7
Rotatable Bonds
4
Heavy Atoms
48
Complexity
1647.5137
Exact Mass
653.41925
Monoisotopic Mass
653.41925
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pregnenolone-naltrexone azine

The XLogP value of 6.7131 indicates that Pregnenolone-naltrexone azine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.88 Ų falls within the moderate polarity range, balancing permeability and solubility for Pregnenolone-naltrexone azine. Following Lipinski's Rule of Five, Pregnenolone-naltrexone azine has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pregnenolone-naltrexone azine?

The CAS number of Pregnenolone-naltrexone azine is 108743-74-4.

What is the molecular formula of Pregnenolone-naltrexone azine?

The molecular formula of Pregnenolone-naltrexone azine is C41H55N3O4.

What is the molecular weight of Pregnenolone-naltrexone azine?

The molecular weight of Pregnenolone-naltrexone azine is 653.42 g/mol.

Where can I buy Pregnenolone-naltrexone azine?

You can request a quote for Pregnenolone-naltrexone azine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pregnenolone-naltrexone azine?

Yes, KEHONG BIO provides custom synthesis services for Pregnenolone-naltrexone azine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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