Meapa-acivicin
TL;DR: Meapa-acivicin (CAS 108743-20-0) is a chemical compound with molecular formula C20H20ClN9O4 and molecular weight 485.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]acetic acid
Also Known As: Meapa-acivicin, (N-(4-Amino-4-deoxy-N(10)-methylpteroyl)amino)-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, (2S)-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]acetic acid, (2S)-[(5S)-3-Chloro-4,5-dihydro-1,2-oxazol-5-yl](4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)acetic acid, 5-Isoxazoleacetic acid, 3-chloro-alpha-((4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)amino)-4,5-dihydro-, (S-(R*,R*))-
| Molecular Formula | C20H20ClN9O4 |
|---|---|
| Molecular Weight | 485.13 g/mol |
| LogP | -1.0 |
| Topological Polar Surface Area | 195.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 7 |
| Exact Mass | 485.1327 |
| Heavy Atoms | 34 |
| Complexity | 781.0 |
Chemical Identifiers
| CAS Number | 108743-20-0 |
|---|---|
| SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H]([C@@H]4CC(=NO4)Cl)C(=O)O |
| InChIKey | KIHCGQIJXRDSSP-JSGCOSHPSA-N |
Product Overview
Meapa-acivicin (CAS 108743-20-0), with molecular formula C20H20ClN9O4 and molecular weight 485.13 g/mol. IUPAC: (2S)-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]acetic acid.
Chemical Property Profile of Meapa-acivicin
Property Insights of Meapa-acivicin
The XLogP value of -1.0 indicates that Meapa-acivicin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 195.0 Ų indicates high polarity, suggesting Meapa-acivicin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Meapa-acivicin has 4 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Meapa-acivicin?
The CAS number of Meapa-acivicin is 108743-20-0.
What is the molecular formula of Meapa-acivicin?
The molecular formula of Meapa-acivicin is C20H20ClN9O4.
What is the molecular weight of Meapa-acivicin?
The molecular weight of Meapa-acivicin is 485.13 g/mol.
Where can I buy Meapa-acivicin?
You can request a quote for Meapa-acivicin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Meapa-acivicin?
Yes, KEHONG BIO provides custom synthesis services for Meapa-acivicin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.