4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-
TL;DR: 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- (CAS 108612-70-0) is a chemical compound with molecular formula C25H24F4N6O and molecular weight 500.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[1-[1-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one
Also Known As: 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-, 2-[[1-[1-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one, 2-{[1-(1-{[4-Fluoro-3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzimidazol-2-yl)piperidin-4-yl](methyl)amino}pyrimidin-4(3H)-one, RefChem:283551
| Molecular Formula | C25H24F4N6O |
|---|---|
| Molecular Weight | 500.19 g/mol |
| LogP | 4.431 |
| Topological Polar Surface Area | 70.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 500.19476 |
| Heavy Atoms | 36 |
| Complexity | 1438.5063 |
Chemical Identifiers
| CAS Number | 108612-70-0 |
|---|---|
| SMILES | CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC(=C(C=C4)F)C(F)(F)F)C5=NC=CC(=O)N5 |
Product Overview
4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- (CAS 108612-70-0), with molecular formula C25H24F4N6O and molecular weight 500.19 g/mol. IUPAC: 2-[[1-[1-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one.
Chemical Property Profile of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-
Property Insights of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-
The XLogP value of 4.431 indicates that 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.05 Ų falls within the moderate polarity range, balancing permeability and solubility for 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-. Following Lipinski's Rule of Five, 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-?
The CAS number of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- is 108612-70-0.
What is the molecular formula of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-?
The molecular formula of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- is C25H24F4N6O.
What is the molecular weight of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-?
The molecular weight of 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- is 500.19 g/mol.
Where can I buy 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-?
You can request a quote for 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)-?
Yes, KEHONG BIO provides custom synthesis services for 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluoro-3-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-piperidinyl)methylamino)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.