RefChem:283627
TL;DR: RefChem:283627 (CAS 108612-66-4) is a chemical compound with molecular formula C25H25F3N6O and molecular weight 482.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[methyl-[1-[1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]piperidin-4-yl]amino]-1H-pyrimidin-6-one
Also Known As: 4(1H)-Pyrimidonone, 2-(methyl(1-(1-((4-(trifluoromethyl)phenyl)methyl)-1H-benzimidazol-2-yl)-4-piperidinyl)amino)-, 2-[methyl-[1-[1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]piperidin-4-yl]amino]-1H-pyrimidin-6-one, 2-{Methyl[1-(1-{[4-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzimidazol-2-yl)piperidin-4-yl]amino}pyrimidin-4(3H)-one, RefChem:283627
| Molecular Formula | C25H25F3N6O |
|---|---|
| Molecular Weight | 482.20 g/mol |
| LogP | 4.2919 |
| Topological Polar Surface Area | 70.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 482.2042 |
| Heavy Atoms | 35 |
| Complexity | 1370.4788 |
Chemical Identifiers
| CAS Number | 108612-66-4 |
|---|---|
| SMILES | CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)C(F)(F)F)C5=NC=CC(=O)N5 |
Product Overview
RefChem:283627 (CAS 108612-66-4), with molecular formula C25H25F3N6O and molecular weight 482.20 g/mol. IUPAC: 2-[methyl-[1-[1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]piperidin-4-yl]amino]-1H-pyrimidin-6-one.
Chemical Property Profile of RefChem:283627
Property Insights of RefChem:283627
The XLogP value of 4.2919 indicates that RefChem:283627 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.05 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:283627. Following Lipinski's Rule of Five, RefChem:283627 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:283627?
The CAS number of RefChem:283627 is 108612-66-4.
What is the molecular formula of RefChem:283627?
The molecular formula of RefChem:283627 is C25H25F3N6O.
What is the molecular weight of RefChem:283627?
The molecular weight of RefChem:283627 is 482.20 g/mol.
Where can I buy RefChem:283627?
You can request a quote for RefChem:283627 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:283627?
Yes, KEHONG BIO provides custom synthesis services for RefChem:283627 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.