6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline
TL;DR: 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline (CAS 108440-32-0) is a chemical compound with molecular formula C9H5ClF3NO2 and molecular weight 251.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-3-hydroxy-3-(trifluoromethyl)-1H-indol-2-one
Also Known As: 6-CHLORO-3-HYDROXY-2-OXO-3-(TRIFLUOROMETHYL)INDOLINE, 6-chloro-3-hydroxy-3-(trifluoromethyl)indolin-2-one, 6-chloro-3-hydroxy-3-(trifluoromethyl)-1H-indol-2-one, AE-848/32729013, 3-hydroxy-2-oxo-3-trifluoromethyl-6-chloroindoline
| Molecular Formula | C9H5ClF3NO2 |
|---|---|
| Molecular Weight | 251.00 g/mol |
| LogP | 2.042 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 250.9961 |
| Heavy Atoms | 16 |
| Complexity | 474.31216 |
Chemical Identifiers
| CAS Number | 108440-32-0 |
|---|---|
| SMILES | C1=CC2=C(C=C1Cl)NC(=O)C2(C(F)(F)F)O |
Product Overview
6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline (CAS 108440-32-0), with molecular formula C9H5ClF3NO2 and molecular weight 251.00 g/mol. IUPAC: 6-chloro-3-hydroxy-3-(trifluoromethyl)-1H-indol-2-one.
Chemical Property Profile of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline
Property Insights of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline
The XLogP value of 2.042 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline. With a topological polar surface area (TPSA) of 49.33 Ų, 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline?
The CAS number of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline is 108440-32-0.
What is the molecular formula of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline?
The molecular formula of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline is C9H5ClF3NO2.
What is the molecular weight of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline?
The molecular weight of 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline is 251.00 g/mol.
Where can I buy 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline?
You can request a quote for 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline?
Yes, KEHONG BIO provides custom synthesis services for 6-Chloro-3-hydroxy-2-oxo-3-(trifluoromethyl)indoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.