RO 23-6152 structure

RO 23-6152

TL;DR: RO 23-6152 (CAS 108383-96-6) is a chemical compound with molecular formula C26H29ClN2O4S and molecular weight 500.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrobenzo[i][1,5]benzothiazepin-3-yl] acetate;hydrochloride

Also Known As: NALTIAZEM HYDROCHLORIDE, Naltiazem (hydrochloride), Ro-23-6152/001, (+)-cis-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-(2-(dimethylamino)ethyl)naptho-(1,2-b)-1,4-thiazepin-4(5H)one HCl, [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrobenzo[i][1,5]benzothiazepin-3-yl] acetate;hydrochloride

CAS: 108383-96-6
Molecular Formula C26H29ClN2O4S
Molecular Weight 500.15 g/mol
LogP 4.9435
Topological Polar Surface Area 84.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 7
Exact Mass 500.15366
Heavy Atoms 34
Complexity 681.0

Chemical Identifiers

CAS Number 108383-96-6
SMILES CC(=O)O[C@@H]1[C@@H](SC2=C(C=CC3=CC=CC=C32)N(C1=O)CCN(C)C)C4=CC=C(C=C4)OC.Cl
InChIKey SFTBZKFGODNAKF-ITNPDYSASA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

RO 23-6152 (CAS 108383-96-6), with molecular formula C26H29ClN2O4S and molecular weight 500.15 g/mol. IUPAC: [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrobenzo[i][1,5]benzothiazepin-3-yl] acetate;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RO 23-6152

XLogP
4.9435
TPSA (Topological Polar Surface Area)
84.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
7
Heavy Atoms
34
Complexity
681.0
Exact Mass
500.15366
Monoisotopic Mass
500.15366
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RO 23-6152

The XLogP value of 4.9435 indicates that RO 23-6152 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.4 Ų falls within the moderate polarity range, balancing permeability and solubility for RO 23-6152. Following Lipinski's Rule of Five, RO 23-6152 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RO 23-6152?

The CAS number of RO 23-6152 is 108383-96-6.

What is the molecular formula of RO 23-6152?

The molecular formula of RO 23-6152 is C26H29ClN2O4S.

What is the molecular weight of RO 23-6152?

The molecular weight of RO 23-6152 is 500.15 g/mol.

Where can I buy RO 23-6152?

You can request a quote for RO 23-6152 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RO 23-6152?

Yes, KEHONG BIO provides custom synthesis services for RO 23-6152 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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