Crlx101
TL;DR: Crlx101 (CAS 1083-11-0) is a chemical compound with molecular formula C20H16N2O4 and molecular weight 348.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19R)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Also Known As: 20R-Camptothecin, (R)-Camptothecin, (R)-(-)-Camptothecin, camptothecin, crlx101
| Molecular Formula | C20H16N2O4 |
|---|---|
| Molecular Weight | 348.11 g/mol |
| LogP | 1.0 |
| Topological Polar Surface Area | 79.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 348.111 |
| Heavy Atoms | 26 |
| Complexity | 742.0 |
Chemical Identifiers
| CAS Number | 1083-11-0 |
|---|---|
| SMILES | CC[C@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O |
| InChIKey | VSJKWCGYPAHWDS-HXUWFJFHSA-N |
Product Overview
Crlx101 (CAS 1083-11-0), with molecular formula C20H16N2O4 and molecular weight 348.11 g/mol. IUPAC: (19R)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of Crlx101
Property Insights of Crlx101
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Crlx101. The TPSA of 79.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Crlx101. Following Lipinski's Rule of Five, Crlx101 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Crlx101?
The CAS number of Crlx101 is 1083-11-0.
What is the molecular formula of Crlx101?
The molecular formula of Crlx101 is C20H16N2O4.
What is the molecular weight of Crlx101?
The molecular weight of Crlx101 is 348.11 g/mol.
Where can I buy Crlx101?
You can request a quote for Crlx101 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Crlx101?
Yes, KEHONG BIO provides custom synthesis services for Crlx101 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.