![(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide structure](/static/products/108/1082668-56-1.png)
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide
概要：(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide（CAS 1082668-56-1）是一种化学化合物，分子式为C18H17ClFN3OS，分子量为377.08 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(1R,9R)-N-(3-chloro-4-fluorophenyl)-6-oxo-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-diene-11-carbothioamide
又称：(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide
| 分子式 | C18H17ClFN3OS |
|---|---|
| 分子量 | 377.08 g/mol |
| LogP | 3.4569 |
| 拓扑极性表面积 | 37.27 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 2 |
| 可旋转键数 | 1 |
| 精确质量 | 377.07648 |
| 重原子数 | 25 |
| 复杂度 | 900.1302 |
化学标识符
| CAS 编号 | 1082668-56-1 |
|---|---|
| SMILES | C1[C@H]2CN(C[C@@H]1C3=CC=CC(=O)N3C2)C(=S)NC4=CC(=C(C=C4)F)Cl |
产品概述
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide（CAS 1082668-56-1），分子式为C18H17ClFN3OS，分子量为377.08 g/mol。IUPAC名：(1R,9R)-N-(3-chloro-4-fluorophenyl)-6-oxo-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-diene-11-carbothioamide。
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide化学性质概览
属性洞察：(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的XLogP值为3.4569，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 (1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的拓扑极性表面积（TPSA）为37.27 Ų，极性较低，可能具有较好的细胞膜透过性。 根据Lipinski五规则，(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide有1个氢键供体和2个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的CAS号是多少？
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的CAS号为1082668-56-1。
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的分子式是什么？
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的分子式为C18H17ClFN3OS。
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的分子量是多少？
(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的分子量为377.08 g/mol。
在哪里可以购买(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide？
您可以直接向科弘生物询价(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide的定制合成服务？
是的，科弘生物提供(1R,5R)-N-(3-chloro-4-fluorophenyl)-8-oxo-4,5,6,8-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(2H)-carbothioamide及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。