4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide structure

4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide

TL;DR: 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide (CAS 107535-40-0) is a chemical compound with molecular formula C22H32N8O5 and molecular weight 488.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-N-[2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-5-oxopyrrolidine-2-carboxamide

Also Known As: Antho-rfamide, Pglu-gly-arg-phe-amide, Pglu-gly-arg-phe-NH2, Pyr-GRF-NH2, ANTHO - RFAMIDE

CAS: 107535-40-0
Molecular Formula C22H32N8O5
Molecular Weight 488.25 g/mol
LogP -2.8676
Topological Polar Surface Area 223.89 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 6
Rotatable Bonds 13
Exact Mass 488.24957
Heavy Atoms 35
Complexity 948.4243

Chemical Identifiers

CAS Number 107535-40-0
SMILES C1CC(=O)N[C@@H]1C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N

Product Overview

4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide (CAS 107535-40-0), with molecular formula C22H32N8O5 and molecular weight 488.25 g/mol. IUPAC: (2S)-N-[2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-5-oxopyrrolidine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide

XLogP
-2.8676
TPSA (Topological Polar Surface Area)
223.89
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
6
Rotatable Bonds
13
Heavy Atoms
35
Complexity
948.4243
Exact Mass
488.24957
Monoisotopic Mass
488.24957
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide

The XLogP value of -2.8676 indicates that 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 223.89 Ų indicates high polarity, suggesting 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide has 7 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide?

The CAS number of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide is 107535-40-0.

What is the molecular formula of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide?

The molecular formula of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide is C22H32N8O5.

What is the molecular weight of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide?

The molecular weight of 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide is 488.25 g/mol.

Where can I buy 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide?

You can request a quote for 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide?

Yes, KEHONG BIO provides custom synthesis services for 4-Pyroglutamyl-glycyl-arginyl-phenylalaninamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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