Saframycin Y2b structure

Saframycin Y2b

TL;DR: Saframycin Y2b (CAS 107140-34-1) is a chemical compound with molecular formula C58H64N10O14 and molecular weight 1124.46 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-amino-N-[[(1S,2S,10R,12R,13R,14S)-12-cyano-14-[[(2S)-1-[[(1S,2S,10R,12R,13R)-12-cyano-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraen-10-yl]methylamino]-1-oxopropan-2-yl]amino]-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraen-10-yl]methyl]propanamide

Also Known As: Saframycin Y2b, Saframycin Y2-b, (2S)-2-amino-N-[[(1S,2S,10R,12R,13R,14S)-12-cyano-14-[[(2S)-1-[[(1S,2S,10R,12R,13R)-12-cyano-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraen-10-yl]methylamino]-1-oxopropan-2-yl]amino]-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraen-10-yl]methyl]propanamide, Propanamide, 2-amino-N-((7-cyano-5-((2-(((7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)amino)-1-methyl-2-oxoethyl)amino)-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-, (5S-(5alpha(R*(6R*,7S*,9S*,14aR*,15S*),6alpha,7alpha,9beta(R*),14aalpha,15alpha)))-

CAS: 107140-34-1
Molecular Formula C58H64N10O14
Molecular Weight 1124.46 g/mol
LogP -1.15944
Topological Polar Surface Area 330.27 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 22
Rotatable Bonds 12
Exact Mass 1124.4603
Heavy Atoms 82
Complexity 3449.2158

Chemical Identifiers

CAS Number 107140-34-1
SMILES CC1=C(C(=O)C2=C(C1=O)C[C@H]3[C@@H]4C5=C([C@@H]([C@@H](N4C)[C@@H](N3[C@H]2CNC(=O)[C@H](C)N)C#N)N[C@@H](C)C(=O)NC[C@H]6C7=C(C[C@@H]8N6[C@H]([C@H]9CC1=C([C@@H]8N9C)C(=O)C(=C(C1=O)C)OC)C#N)C(=O)C(=C(C7=O)OC)C)C(=O)C(=C(C5=O)OC)C)OC

Product Overview

Saframycin Y2b (CAS 107140-34-1), with molecular formula C58H64N10O14 and molecular weight 1124.46 g/mol. IUPAC: (2S)-2-amino-N-[[(1S,2S,10R,12R,13R,14S)-12-cyano-14-[[(2S)-1-[[(1S,2S,10R,12R,13R)-12-cyano-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraen-10-yl]methylamino]-1-oxopropan-2-yl]amino]-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraen-10-yl]methyl]propanamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Saframycin Y2b

XLogP
-1.15944
TPSA (Topological Polar Surface Area)
330.27
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
22
Rotatable Bonds
12
Heavy Atoms
82
Complexity
3449.2158
Exact Mass
1124.4603
Monoisotopic Mass
1124.4603
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Saframycin Y2b

The XLogP value of -1.15944 indicates that Saframycin Y2b is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 330.27 Ų indicates high polarity, suggesting Saframycin Y2b may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Saframycin Y2b has 4 hydrogen bond donor(s) and 22 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Saframycin Y2b?

The CAS number of Saframycin Y2b is 107140-34-1.

What is the molecular formula of Saframycin Y2b?

The molecular formula of Saframycin Y2b is C58H64N10O14.

What is the molecular weight of Saframycin Y2b?

The molecular weight of Saframycin Y2b is 1124.46 g/mol.

Where can I buy Saframycin Y2b?

You can request a quote for Saframycin Y2b directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Saframycin Y2b?

Yes, KEHONG BIO provides custom synthesis services for Saframycin Y2b and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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