4-Hydroxy Nisoldipine
TL;DR: 4-Hydroxy Nisoldipine (CAS 106685-70-5) is a chemical compound with molecular formula C20H24N2O7 and molecular weight 404.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-(2-hydroxy-2-methylpropyl) 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: 4-Hydroxy Nisoldipine, BAY-r-9425, NISOLDIPINE (M9), BAY-r 9425, 5-O-(2-hydroxy-2-methylpropyl) 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
| Molecular Formula | C20H24N2O7 |
|---|---|
| Molecular Weight | 404.16 g/mol |
| LogP | 1.9 |
| Topological Polar Surface Area | 131.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 404.15836 |
| Heavy Atoms | 29 |
| Complexity | 748.0 |
Chemical Identifiers
| CAS Number | 106685-70-5 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCC(C)(C)O)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC |
| InChIKey | MOZPKZYMNVFLSU-UHFFFAOYSA-N |
Product Overview
4-Hydroxy Nisoldipine (CAS 106685-70-5), with molecular formula C20H24N2O7 and molecular weight 404.16 g/mol. IUPAC: 5-O-(2-hydroxy-2-methylpropyl) 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 4-Hydroxy Nisoldipine
Property Insights of 4-Hydroxy Nisoldipine
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Hydroxy Nisoldipine. The TPSA of 131.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Hydroxy Nisoldipine. Following Lipinski's Rule of Five, 4-Hydroxy Nisoldipine has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Hydroxy Nisoldipine?
The CAS number of 4-Hydroxy Nisoldipine is 106685-70-5.
What is the molecular formula of 4-Hydroxy Nisoldipine?
The molecular formula of 4-Hydroxy Nisoldipine is C20H24N2O7.
What is the molecular weight of 4-Hydroxy Nisoldipine?
The molecular weight of 4-Hydroxy Nisoldipine is 404.16 g/mol.
Where can I buy 4-Hydroxy Nisoldipine?
You can request a quote for 4-Hydroxy Nisoldipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Hydroxy Nisoldipine?
Yes, KEHONG BIO provides custom synthesis services for 4-Hydroxy Nisoldipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.