H-152/81
TL;DR: H-152/81 (CAS 105580-49-2) is a chemical compound with molecular formula C16H15Cl2NO4 and molecular weight 355.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2,3-dichlorophenyl)-5-methoxycarbonyl-2,6-dimethyl-1,4-dihydropyridine-3-carboxylic acid
Also Known As: Desethyl Felodipine, 4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylic acid, Felodipine Impurity 6, Clevidipine Impurity A, Clevidipine Impurity 1
| Molecular Formula | C16H15Cl2NO4 |
|---|---|
| Molecular Weight | 355.04 g/mol |
| LogP | 3.4858 |
| Topological Polar Surface Area | 75.63 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 355.0378 |
| Heavy Atoms | 23 |
| Complexity | 752.44714 |
Chemical Identifiers
| CAS Number | 105580-49-2 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl)C(=O)O |
Product Overview
H-152/81 (CAS 105580-49-2), with molecular formula C16H15Cl2NO4 and molecular weight 355.04 g/mol. IUPAC: 4-(2,3-dichlorophenyl)-5-methoxycarbonyl-2,6-dimethyl-1,4-dihydropyridine-3-carboxylic acid.
Chemical Property Profile of H-152/81
Property Insights of H-152/81
The XLogP value of 3.4858 indicates that H-152/81 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.63 Ų falls within the moderate polarity range, balancing permeability and solubility for H-152/81. Following Lipinski's Rule of Five, H-152/81 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of H-152/81?
The CAS number of H-152/81 is 105580-49-2.
What is the molecular formula of H-152/81?
The molecular formula of H-152/81 is C16H15Cl2NO4.
What is the molecular weight of H-152/81?
The molecular weight of H-152/81 is 355.04 g/mol.
Where can I buy H-152/81?
You can request a quote for H-152/81 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for H-152/81?
Yes, KEHONG BIO provides custom synthesis services for H-152/81 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.