3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone
TL;DR: 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone (CAS 105316-81-2) is a chemical compound with molecular formula C13H12N2OS and molecular weight 244.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(2-methyl-1,3-thiazol-4-yl)-3,4-dihydro-1H-quinolin-2-one
Also Known As: Maybridge1_001848, 6-(2-methylthiazol-4-yl)-3,4-dihydroquinolin-2(1H)-one, 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone, 6-(2-methyl-1,3-thiazol-4-yl)-3,4-dihydro-1H-quinolin-2-one, 6-(2-methyl-1,3-thiazol-4-yl)-1,2,3,4-tetrahydro-2-quinolinone
| Molecular Formula | C13H12N2OS |
|---|---|
| Molecular Weight | 244.07 g/mol |
| LogP | 3.00322 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.06703 |
| Heavy Atoms | 17 |
| Complexity | 588.85547 |
Chemical Identifiers
| CAS Number | 105316-81-2 |
|---|---|
| SMILES | CC1=NC(=CS1)C2=CC3=C(C=C2)NC(=O)CC3 |
Product Overview
3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone (CAS 105316-81-2), with molecular formula C13H12N2OS and molecular weight 244.07 g/mol. IUPAC: 6-(2-methyl-1,3-thiazol-4-yl)-3,4-dihydro-1H-quinolin-2-one.
Chemical Property Profile of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone
Property Insights of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone
The XLogP value of 3.00322 indicates that 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone?
The CAS number of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone is 105316-81-2.
What is the molecular formula of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone?
The molecular formula of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone is C13H12N2OS.
What is the molecular weight of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone?
The molecular weight of 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone is 244.07 g/mol.
Where can I buy 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone?
You can request a quote for 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone?
Yes, KEHONG BIO provides custom synthesis services for 3,4-Dihydro-6-(2-methyl-4-thiazolyl)-2(1H)-quinolinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.