1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
TL;DR: 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil (CAS 105281-08-1) is a chemical compound with molecular formula C9H11FN2O4 and molecular weight 230.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidine-2,4-dione
Also Known As: 5'-deoxy-FAU, 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil, J3.415.011G, 1-(2,5-Dideoxy-2-fluoro-.beta.-D-arabinofuranosyl)uracil, 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione
| Molecular Formula | C9H11FN2O4 |
|---|---|
| Molecular Weight | 230.07 g/mol |
| LogP | -0.5 |
| Topological Polar Surface Area | 78.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 230.07028 |
| Heavy Atoms | 16 |
| Complexity | 359.0 |
Chemical Identifiers
| CAS Number | 105281-08-1 |
|---|---|
| SMILES | C[C@@H]1[C@H]([C@@H]([C@@H](O1)N2C=CC(=O)NC2=O)F)O |
| InChIKey | XKBSNQZIXJSHIG-PXBUCIJWSA-N |
Product Overview
1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil (CAS 105281-08-1), with molecular formula C9H11FN2O4 and molecular weight 230.07 g/mol. IUPAC: 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
Property Insights of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
The XLogP value of -0.5 indicates that 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil. Following Lipinski's Rule of Five, 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil?
The CAS number of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is 105281-08-1.
What is the molecular formula of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil?
The molecular formula of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is C9H11FN2O4.
What is the molecular weight of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil?
The molecular weight of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is 230.07 g/mol.
Where can I buy 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil?
You can request a quote for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil?
Yes, KEHONG BIO provides custom synthesis services for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.