RefChem:385471 structure

RefChem:385471

TL;DR: RefChem:385471 (CAS 105271-21-4) is a chemical compound with molecular formula C24H22N4O2S and molecular weight 430.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[3-methoxy-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]-3-(4-methylphenyl)thiourea

Also Known As: Thiourea, N-(3-methoxy-4-(2-methyl-4-oxo-3(4H)-quinazolinyl)phenyl)-N'-(4-methylphenyl)-, N-(3-Methoxy-4-(2-methyl-4-oxo-3(4H)-quinazolinyl)phenyl)-N'-(4-methylphenyl)thiourea, 1-[3-methoxy-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]-3-(4-methylphenyl)thiourea, N-[3-Methoxy-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl]-N'-(4-methylphenyl)thiourea, RefChem:385471

CAS: 105271-21-4
Molecular Formula C24H22N4O2S
Molecular Weight 430.15 g/mol
LogP 4.82004
Topological Polar Surface Area 68.18 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 430.14636
Heavy Atoms 31
Complexity 1329.9885

Chemical Identifiers

CAS Number 105271-21-4
SMILES CC1=CC=C(C=C1)NC(=S)NC2=CC(=C(C=C2)N3C(=NC4=CC=CC=C4C3=O)C)OC

Product Overview

RefChem:385471 (CAS 105271-21-4), with molecular formula C24H22N4O2S and molecular weight 430.15 g/mol. IUPAC: 1-[3-methoxy-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]-3-(4-methylphenyl)thiourea.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:385471

XLogP
4.82004
TPSA (Topological Polar Surface Area)
68.18
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
31
Complexity
1329.9885
Exact Mass
430.14636
Monoisotopic Mass
430.14636
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:385471

The XLogP value of 4.82004 indicates that RefChem:385471 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.18 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:385471. Following Lipinski's Rule of Five, RefChem:385471 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:385471?

The CAS number of RefChem:385471 is 105271-21-4.

What is the molecular formula of RefChem:385471?

The molecular formula of RefChem:385471 is C24H22N4O2S.

What is the molecular weight of RefChem:385471?

The molecular weight of RefChem:385471 is 430.15 g/mol.

Where can I buy RefChem:385471?

You can request a quote for RefChem:385471 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:385471?

Yes, KEHONG BIO provides custom synthesis services for RefChem:385471 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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