Reboxetine
TL;DR: Reboxetine (CAS 105017-38-7) is a chemical compound with molecular formula C19H23NO3 and molecular weight 313.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine
Also Known As: Reboxetine, Reboxitine, Edronax, Norebox, Vestra
| Molecular Formula | C19H23NO3 |
|---|---|
| Molecular Weight | 313.17 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 39.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 313.1678 |
| Heavy Atoms | 23 |
| Complexity | 333.0 |
| Melting Point | 170-171 °C (Mesylate salt) |
| Solubility | 8 |
Chemical Identifiers
| CAS Number | 105017-38-7 |
|---|---|
| SMILES | CCOC1=CC=CC=C1O[C@@H]([C@H]2CNCCO2)C3=CC=CC=C3 |
| InChIKey | CBQGYUDMJHNJBX-RTBURBONSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Reboxetine (CAS 105017-38-7), with molecular formula C19H23NO3 and molecular weight 313.17 g/mol. IUPAC: (2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine.
Chemical Property Profile of Reboxetine
Property Insights of Reboxetine
The XLogP value of 3.0 indicates that Reboxetine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.7 Ų, Reboxetine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Reboxetine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Reboxetine?
The CAS number of Reboxetine is 105017-38-7.
What is the molecular formula of Reboxetine?
The molecular formula of Reboxetine is C19H23NO3.
What is the molecular weight of Reboxetine?
The molecular weight of Reboxetine is 313.17 g/mol.
Where can I buy Reboxetine?
You can request a quote for Reboxetine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Reboxetine?
Yes, KEHONG BIO provides custom synthesis services for Reboxetine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.