Diethyl Malonate structure

Diethyl Malonate

TL;DR: Diethyl Malonate (CAS 105-53-3) is a chemical compound with molecular formula C7H12O4 and molecular weight 160.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

diethyl propanedioate

Also Known As: DIETHYL MALONATE, Diethyl propanedioate, Ethyl malonate, Malonic ester, Dicarbethoxymethane

CAS: 105-53-3
Molecular Formula C7H12O4
Molecular Weight 160.07 g/mol
LogP 1.0
Topological Polar Surface Area 52.6 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 160.07356
Heavy Atoms 11
Complexity 125.0
Melting Point -50 °C
Boiling Point 200 °C
Density 1.0551 g/cu cm at 20 °C
Solubility In water, 20 g/L at 20 °C
Flash Point 93.3 °C (93 °C) (open cup)
Vapor Pressure 0.26 [mmHg]
Refractive Index 1.4139 at 20 °C

Chemical Identifiers

CAS Number 105-53-3
SMILES CCOC(=O)CC(=O)OCC
InChIKey IYXGSMUGOJNHAZ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 22 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (993 patents) Analytical Reagents (242 patents) Biotechnology (289 patents) Catalysts (302 patents) Coatings & Adhesives (1070 patents) +17 more

Product Overview

Diethyl Malonate (CAS 105-53-3), with molecular formula C7H12O4 and molecular weight 160.07 g/mol. IUPAC: diethyl propanedioate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Diethyl Malonate

XLogP
1.0
TPSA (Topological Polar Surface Area)
52.6
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
11
Complexity
125.0
Exact Mass
160.07356
Monoisotopic Mass
160.07356
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diethyl Malonate

The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Diethyl Malonate. With a topological polar surface area (TPSA) of 52.6 Ų, Diethyl Malonate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diethyl Malonate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diethyl Malonate?

The CAS number of Diethyl Malonate is 105-53-3.

What is the molecular formula of Diethyl Malonate?

The molecular formula of Diethyl Malonate is C7H12O4.

What is the molecular weight of Diethyl Malonate?

The molecular weight of Diethyl Malonate is 160.07 g/mol.

Where can I buy Diethyl Malonate?

You can request a quote for Diethyl Malonate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diethyl Malonate?

Yes, KEHONG BIO provides custom synthesis services for Diethyl Malonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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