RefChem:377425
TL;DR: RefChem:377425 (CAS 104964-25-2) is a chemical compound with molecular formula C22H25ClN8O3 and molecular weight 484.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-6-methylpyrido[4,3-d]pyrimidin-5-one;hydrochloride
Also Known As: Pyrido(4,3-d)pyrimidin-5(6H)-one, 2-(4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl)-6-methyl-, hydrochloride, 2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-6-methylpyrido[4,3-d]pyrimidin-5-one hydrochloride, 2-[4-(4-Imino-6,7-dimethoxy-3,4-dihydroquinazolin-2-yl)piperazin-1-yl]-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one--hydrogen chloride (1/1), RefChem:377425
| Molecular Formula | C22H25ClN8O3 |
|---|---|
| Molecular Weight | 484.17 g/mol |
| LogP | 1.6195 |
| Topological Polar Surface Area | 124.52 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 4 |
| Exact Mass | 484.17383 |
| Heavy Atoms | 34 |
| Complexity | 1419.1964 |
Chemical Identifiers
| CAS Number | 104964-25-2 |
|---|---|
| SMILES | CN1C=CC2=NC(=NC=C2C1=O)N3CCN(CC3)C4=NC5=CC(=C(C=C5C(=N4)N)OC)OC.Cl |
Product Overview
RefChem:377425 (CAS 104964-25-2), with molecular formula C22H25ClN8O3 and molecular weight 484.17 g/mol. IUPAC: 2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-6-methylpyrido[4,3-d]pyrimidin-5-one;hydrochloride.
Chemical Property Profile of RefChem:377425
Property Insights of RefChem:377425
The XLogP value of 1.6195 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RefChem:377425. The TPSA of 124.52 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:377425. Following Lipinski's Rule of Five, RefChem:377425 has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:377425?
The CAS number of RefChem:377425 is 104964-25-2.
What is the molecular formula of RefChem:377425?
The molecular formula of RefChem:377425 is C22H25ClN8O3.
What is the molecular weight of RefChem:377425?
The molecular weight of RefChem:377425 is 484.17 g/mol.
Where can I buy RefChem:377425?
You can request a quote for RefChem:377425 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:377425?
Yes, KEHONG BIO provides custom synthesis services for RefChem:377425 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.