TOPOTECAN HYDROCHLORIDE
TL;DR: TOPOTECAN HYDROCHLORIDE (CAS 1044746-98-6) is a chemical compound with molecular formula C23H24ClN3O5 and molecular weight 457.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
Also Known As: TOPOTECAN HYDROCHLORIDE, Hycamtin, Topotecan Hcl, Topotecan-d6 Hydrochloride, Topotecan Hydrochloride [M+H]+
| Molecular Formula | C23H24ClN3O5 |
|---|---|
| Molecular Weight | 457.14 g/mol |
| LogP | 2.2686 |
| Topological Polar Surface Area | 104.89 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 457.14044 |
| Heavy Atoms | 32 |
| Complexity | 1333.682 |
Chemical Identifiers
| CAS Number | 1044746-98-6 |
|---|---|
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl |
Product Overview
TOPOTECAN HYDROCHLORIDE (CAS 1044746-98-6), with molecular formula C23H24ClN3O5 and molecular weight 457.14 g/mol. IUPAC: 8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride.
Chemical Property Profile of TOPOTECAN HYDROCHLORIDE
Property Insights of TOPOTECAN HYDROCHLORIDE
The XLogP value of 2.2686 suggests moderate lipophilicity, balancing water solubility and membrane permeability for TOPOTECAN HYDROCHLORIDE. The TPSA of 104.89 Ų falls within the moderate polarity range, balancing permeability and solubility for TOPOTECAN HYDROCHLORIDE. Following Lipinski's Rule of Five, TOPOTECAN HYDROCHLORIDE has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TOPOTECAN HYDROCHLORIDE?
The CAS number of TOPOTECAN HYDROCHLORIDE is 1044746-98-6.
What is the molecular formula of TOPOTECAN HYDROCHLORIDE?
The molecular formula of TOPOTECAN HYDROCHLORIDE is C23H24ClN3O5.
What is the molecular weight of TOPOTECAN HYDROCHLORIDE?
The molecular weight of TOPOTECAN HYDROCHLORIDE is 457.14 g/mol.
Where can I buy TOPOTECAN HYDROCHLORIDE?
You can request a quote for TOPOTECAN HYDROCHLORIDE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TOPOTECAN HYDROCHLORIDE?
Yes, KEHONG BIO provides custom synthesis services for TOPOTECAN HYDROCHLORIDE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.