1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine structure

1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine

TL;DR: 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine (CAS 1042444-54-1) is a chemical compound with molecular formula C14H16F3NO2 and molecular weight 287.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[[4-(trifluoromethyl)phenyl]methyl]piperidine-2-carboxylic acid

Also Known As: 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine, 1-[[4-(trifluoromethyl)phenyl]methyl]piperidine-2-carboxylic Acid, 1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxylic

CAS: 1042444-54-1
Molecular Formula C14H16F3NO2
Molecular Weight 287.11 g/mol
LogP 3.1445
Topological Polar Surface Area 40.54 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 287.1133
Heavy Atoms 20
Complexity 470.30252

Chemical Identifiers

CAS Number 1042444-54-1
SMILES C1CCN(C(C1)C(=O)O)CC2=CC=C(C=C2)C(F)(F)F

Product Overview

1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine (CAS 1042444-54-1), with molecular formula C14H16F3NO2 and molecular weight 287.11 g/mol. IUPAC: 1-[[4-(trifluoromethyl)phenyl]methyl]piperidine-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine

XLogP
3.1445
TPSA (Topological Polar Surface Area)
40.54
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
20
Complexity
470.30252
Exact Mass
287.1133
Monoisotopic Mass
287.1133
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine

The XLogP value of 3.1445 indicates that 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.54 Ų, 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine?

The CAS number of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine is 1042444-54-1.

What is the molecular formula of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine?

The molecular formula of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine is C14H16F3NO2.

What is the molecular weight of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine?

The molecular weight of 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine is 287.11 g/mol.

Where can I buy 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine?

You can request a quote for 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-Trifluoromethylbenzyl)-2-carboxypiperidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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