那可丁
TL;DR: 那可丁 (CAS 10421-76-8) is a chemical compound with molecular formula C22H23NO7 and molecular weight 413.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
那可丁
6,7-dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one
Also Known As: noscapine, Gnoscopine, dl-Narcotine, NARCOTINE, Nascopine
| Molecular Formula | C22H23NO7 |
|---|---|
| Molecular Weight | 413.15 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 75.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 413.14746 |
| Heavy Atoms | 30 |
| Complexity | 647.0 |
| Melting Point | 230 - 233 °C |
| Solubility | 0.044 mg/mL at 20 °C |
Chemical Identifiers
| CAS Number | 10421-76-8 |
|---|---|
| SMILES | CN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3 |
| InChIKey | AKNNEGZIBPJZJG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
那可丁 (CAS 10421-76-8), with molecular formula C22H23NO7 and molecular weight 413.15 g/mol. IUPAC: 6,7-dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one.
Chemical Property Profile of 那可丁
Property Insights of 那可丁
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 那可丁. The TPSA of 75.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 那可丁. Following Lipinski's Rule of Five, Gnoscopine has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Gnoscopine?
The CAS number of Gnoscopine is 10421-76-8.
What is the molecular formula of Gnoscopine?
The molecular formula of Gnoscopine is C22H23NO7.
What is the molecular weight of Gnoscopine?
The molecular weight of Gnoscopine is 413.15 g/mol.
Where can I buy Gnoscopine?
You can request a quote for Gnoscopine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Gnoscopine?
Yes, KEHONG BIO provides custom synthesis services for Gnoscopine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.