拉西地平
TL;DR: 拉西地平 (CAS 103890-78-4) is a chemical compound with molecular formula C26H33NO6 and molecular weight 455.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
拉西地平
diethyl 2,6-dimethyl-4-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Lacidipine, Cislacidipine, cis Lacidipine, trans Lacidipine, diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
| Molecular Formula | C26H33NO6 |
|---|---|
| Molecular Weight | 455.23 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 90.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 11 |
| Exact Mass | 455.23077 |
| Heavy Atoms | 33 |
| Complexity | 805.0 |
Chemical Identifiers
| CAS Number | 103890-78-4 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C=CC(=O)OC(C)(C)C)C(=O)OCC)C)C |
| InChIKey | GKQPCPXONLDCMU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
拉西地平 (CAS 103890-78-4), with molecular formula C26H33NO6 and molecular weight 455.23 g/mol. IUPAC: diethyl 2,6-dimethyl-4-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 拉西地平
Property Insights of 拉西地平
The XLogP value of 4.5 indicates that 拉西地平 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 拉西地平. Following Lipinski's Rule of Five, 拉西地平 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 拉西地平?
The CAS number of 拉西地平 is 103890-78-4.
What is the molecular formula of 拉西地平?
The molecular formula of 拉西地平 is C26H33NO6.
What is the molecular weight of 拉西地平?
The molecular weight of 拉西地平 is 455.23 g/mol.
Where can I buy 拉西地平?
You can request a quote for 拉西地平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 拉西地平?
Yes, KEHONG BIO provides custom synthesis services for 拉西地平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.