Prothrombin (18-23) structure

Prothrombin (18-23)

TL;DR: Prothrombin (18-23) (CAS 103658-53-3) is a chemical compound with molecular formula C32H47N7O15S2 and molecular weight 833.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S)-3-[[(2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-4-methylpentanoyl]amino]-4-[(2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]-[(2R)-2-(methylamino)-3-sulfanyl-3-sulfanylidenepropanoyl]carbamoyl]pyrrolidin-1-yl]-4-oxobutane-1,1,1-tricarboxylic acid

Also Known As: Prothrombin (18-23), (3S)-3-[[(2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-4-methylpentanoyl]amino]-4-[(2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]-[(2R)-2-(methylamino)-3-sulfanyl-3-sulfanylidenepropanoyl]carbamoyl]pyrrolidin-1-yl]-4-oxobutane-1,1,1-tricarboxylic acid, (3S)-3-[[(2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-4-methylpentanoyl]amino]-4-[(2S)-2-[[(2S)-2-amino-5-hydroxy-5-oxopentanoyl]-[(2R)-2-(methylamino)-3-sulfanyl-3-sulfanylidenepropanoyl]carbamoyl]pyrrolidin-1-yl]-4-oxobutane-1,1,1-tricarboxylic acid, (3s)-3-[[(2s)-2-[[(2s)-2-acetamidopropanoyl]amino]-4-methylpentanoyl]amino]-4-[(2s)-2-[[(2s)-2-amino-5-hydroxy-5-oxopentanoyl]-[(2r)-2-methylamino-3-sulfanyl-3-sulfanylidenepropanoyl]carbamoyl]pyrrolidin-1-yl]-4-oxobutane-1,1,1-tricarboxylic acid, 4,4-Dicarboxy-N-[(2S)-1-hydroxy-2-({(2S)-1-hydroxy-2-[(1-hydroxyethylidene)amino]propylidene}amino)-4-methylpentylidene]-L-alpha-glutamyl-N-[(2S)-2-amino-4-carboxybutanoyl]-N-[(2R)-2-(methylamino)-3-sulfanyl-3-sulfanylidenepropanoyl]-L-prolinamide

CAS: 103658-53-3
Molecular Formula C32H47N7O15S2
Molecular Weight 833.26 g/mol
LogP -6.3
Topological Polar Surface Area 382.0 Ų
Hydrogen Bond Donors 10
Hydrogen Bond Acceptors 19
Rotatable Bonds 21
Exact Mass 833.25714
Heavy Atoms 56
Complexity 1590.0

Chemical Identifiers

CAS Number 103658-53-3
SMILES C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C(=O)O)(C(=O)O)C(=O)O)C(=O)N1CCC[C@H]1C(=O)N(C(=O)[C@H](CCC(=O)O)N)C(=O)[C@H](C(=S)S)NC)NC(=O)C
InChIKey FSRRFCISZLQALP-NMTCSRCMSA-N

Product Overview

Prothrombin (18-23) (CAS 103658-53-3), with molecular formula C32H47N7O15S2 and molecular weight 833.26 g/mol. IUPAC: (3S)-3-[[(2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-4-methylpentanoyl]amino]-4-[(2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]-[(2R)-2-(methylamino)-3-sulfanyl-3-sulfanylidenepropanoyl]carbamoyl]pyrrolidin-1-yl]-4-oxobutane-1,1,1-tricarboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Prothrombin (18-23)

XLogP
-6.3
TPSA (Topological Polar Surface Area)
382.0
Hydrogen Bond Donors
10
Hydrogen Bond Acceptors
19
Rotatable Bonds
21
Heavy Atoms
56
Complexity
1590.0
Exact Mass
833.25714
Monoisotopic Mass
833.25714
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Prothrombin (18-23)

The XLogP value of -6.3 indicates that Prothrombin (18-23) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 382.0 Ų indicates high polarity, suggesting Prothrombin (18-23) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Prothrombin (18-23) has 10 hydrogen bond donor(s) and 19 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Prothrombin (18-23)?

The CAS number of Prothrombin (18-23) is 103658-53-3.

What is the molecular formula of Prothrombin (18-23)?

The molecular formula of Prothrombin (18-23) is C32H47N7O15S2.

What is the molecular weight of Prothrombin (18-23)?

The molecular weight of Prothrombin (18-23) is 833.26 g/mol.

Where can I buy Prothrombin (18-23)?

You can request a quote for Prothrombin (18-23) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Prothrombin (18-23)?

Yes, KEHONG BIO provides custom synthesis services for Prothrombin (18-23) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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