5'-O-amino-2'-deoxy-5-fluorouridine
TL;DR: 5'-O-amino-2'-deoxy-5-fluorouridine (CAS 103251-31-6) is a chemical compound with molecular formula C9H12FN3O5 and molecular weight 261.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-5-(aminooxymethyl)-4-hydroxyoxolan-2-yl]-5-fluoropyrimidine-2,4-dione
Also Known As: 5'-O-amino-2'-deoxy-5-fluorouridine, uridine, 5'-O-amino-2'-deoxy-5-fluoro-, 1-[(2R,4S,5R)-5-(aminooxymethyl)-4-hydroxy-oxolan-2-yl]-5-fluoro-pyrimidine-2,4-dione
| Molecular Formula | C9H12FN3O5 |
|---|---|
| Molecular Weight | 261.08 g/mol |
| LogP | -1.7856 |
| Topological Polar Surface Area | 119.57 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 261.0761 |
| Heavy Atoms | 18 |
| Complexity | 541.74005 |
Chemical Identifiers
| CAS Number | 103251-31-6 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CON)O |
Product Overview
5'-O-amino-2'-deoxy-5-fluorouridine (CAS 103251-31-6), with molecular formula C9H12FN3O5 and molecular weight 261.08 g/mol. IUPAC: 1-[(2R,4S,5R)-5-(aminooxymethyl)-4-hydroxyoxolan-2-yl]-5-fluoropyrimidine-2,4-dione.
Chemical Property Profile of 5'-O-amino-2'-deoxy-5-fluorouridine
Property Insights of 5'-O-amino-2'-deoxy-5-fluorouridine
The XLogP value of -1.7856 indicates that 5'-O-amino-2'-deoxy-5-fluorouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 119.57 Ų falls within the moderate polarity range, balancing permeability and solubility for 5'-O-amino-2'-deoxy-5-fluorouridine. Following Lipinski's Rule of Five, 5'-O-amino-2'-deoxy-5-fluorouridine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5'-O-amino-2'-deoxy-5-fluorouridine?
The CAS number of 5'-O-amino-2'-deoxy-5-fluorouridine is 103251-31-6.
What is the molecular formula of 5'-O-amino-2'-deoxy-5-fluorouridine?
The molecular formula of 5'-O-amino-2'-deoxy-5-fluorouridine is C9H12FN3O5.
What is the molecular weight of 5'-O-amino-2'-deoxy-5-fluorouridine?
The molecular weight of 5'-O-amino-2'-deoxy-5-fluorouridine is 261.08 g/mol.
Where can I buy 5'-O-amino-2'-deoxy-5-fluorouridine?
You can request a quote for 5'-O-amino-2'-deoxy-5-fluorouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5'-O-amino-2'-deoxy-5-fluorouridine?
Yes, KEHONG BIO provides custom synthesis services for 5'-O-amino-2'-deoxy-5-fluorouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.