Clevudine
TL;DR: Clevudine (CAS 1027764-72-2) is a chemical compound with molecular formula C10H13FN2O5 and molecular weight 260.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: Clevudine, 1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine, 1-(2-Fluoro-2-deoxy-alpha-L-arabinofuranosyl)thymine, 1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
| Molecular Formula | C10H13FN2O5 |
|---|---|
| Molecular Weight | 260.08 g/mol |
| LogP | -1.56628 |
| Topological Polar Surface Area | 104.55 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 260.08084 |
| Heavy Atoms | 18 |
| Complexity | 553.9344 |
Chemical Identifiers
| CAS Number | 1027764-72-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@H]([C@@H](O2)CO)O)F |
Product Overview
Clevudine (CAS 1027764-72-2), with molecular formula C10H13FN2O5 and molecular weight 260.08 g/mol. IUPAC: 1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of Clevudine
Property Insights of Clevudine
The XLogP value of -1.56628 indicates that Clevudine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.55 Ų falls within the moderate polarity range, balancing permeability and solubility for Clevudine. Following Lipinski's Rule of Five, Clevudine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clevudine?
The CAS number of Clevudine is 1027764-72-2.
What is the molecular formula of Clevudine?
The molecular formula of Clevudine is C10H13FN2O5.
What is the molecular weight of Clevudine?
The molecular weight of Clevudine is 260.08 g/mol.
Where can I buy Clevudine?
You can request a quote for Clevudine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clevudine?
Yes, KEHONG BIO provides custom synthesis services for Clevudine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.