2-N-(APPDHP)
TL;DR: 2-N-(APPDHP) (CAS 1026086-99-6) is a chemical compound with molecular formula C24H30F2N4O2 and molecular weight 444.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-N-[1-[(6-amino-2-pyridinyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Also Known As: 2-N-(APPDHP), PDSP1_000792, PDSP2_000780, L-753099, J1.412.619H
| Molecular Formula | C24H30F2N4O2 |
|---|---|
| Molecular Weight | 444.23 g/mol |
| LogP | 3.0676 |
| Topological Polar Surface Area | 91.48 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 444.23367 |
| Heavy Atoms | 32 |
| Complexity | 934.60626 |
Chemical Identifiers
| CAS Number | 1026086-99-6 |
|---|---|
| SMILES | C1CC(C[C@@H]1[C@@](C2=CC=CC=C2)(C(=O)NC3CCN(CC3)CC4=NC(=CC=C4)N)O)(F)F |
Product Overview
2-N-(APPDHP) (CAS 1026086-99-6), with molecular formula C24H30F2N4O2 and molecular weight 444.23 g/mol. IUPAC: (2R)-N-[1-[(6-amino-2-pyridinyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide.
Chemical Property Profile of 2-N-(APPDHP)
Property Insights of 2-N-(APPDHP)
The XLogP value of 3.0676 indicates that 2-N-(APPDHP) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.48 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-N-(APPDHP). Following Lipinski's Rule of Five, 2-N-(APPDHP) has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-N-(APPDHP)?
The CAS number of 2-N-(APPDHP) is 1026086-99-6.
What is the molecular formula of 2-N-(APPDHP)?
The molecular formula of 2-N-(APPDHP) is C24H30F2N4O2.
What is the molecular weight of 2-N-(APPDHP)?
The molecular weight of 2-N-(APPDHP) is 444.23 g/mol.
Where can I buy 2-N-(APPDHP)?
You can request a quote for 2-N-(APPDHP) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-N-(APPDHP)?
Yes, KEHONG BIO provides custom synthesis services for 2-N-(APPDHP) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.