8R-0317 structure

8R-0317

TL;DR: 8R-0317 (CAS 1024618-15-2) is a chemical compound with molecular formula C19H19ClN4O3S2 and molecular weight 450.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[(2-chloro-1,3-thiazol-4-yl)methylsulfanyl]-8,9-dimethoxy-3-propan-2-yl-3H-imidazo[1,2-c]quinazolin-2-one

Also Known As: 8R-0317, 5-{[(2-chloro-1,3-thiazol-4-yl)methyl]sulfanyl}-3-isopropyl-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one, 5-[(2-chloro-1,3-thiazol-4-yl)methylsulfanyl]-8,9-dimethoxy-3-propan-2-yl-3H-imidazo[1,2-c]quinazolin-2-one, 5-{[(2-chloro-1,3-thiazol-4-yl)methyl]sulfanyl}-8,9-dimethoxy-3-(propan-2-yl)-2H,3H-imidazo[1,2-c]quinazolin-2-one

CAS: 1024618-15-2
Molecular Formula C19H19ClN4O3S2
Molecular Weight 450.06 g/mol
LogP 4.3616
Topological Polar Surface Area 76.38 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 5
Exact Mass 450.05872
Heavy Atoms 29
Complexity 1034.4568

Chemical Identifiers

CAS Number 1024618-15-2
SMILES CC(C)C1C(=O)N=C2N1C(=NC3=CC(=C(C=C32)OC)OC)SCC4=CSC(=N4)Cl

Product Overview

8R-0317 (CAS 1024618-15-2), with molecular formula C19H19ClN4O3S2 and molecular weight 450.06 g/mol. IUPAC: 5-[(2-chloro-1,3-thiazol-4-yl)methylsulfanyl]-8,9-dimethoxy-3-propan-2-yl-3H-imidazo[1,2-c]quinazolin-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8R-0317

XLogP
4.3616
TPSA (Topological Polar Surface Area)
76.38
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
5
Heavy Atoms
29
Complexity
1034.4568
Exact Mass
450.05872
Monoisotopic Mass
450.05872
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8R-0317

The XLogP value of 4.3616 indicates that 8R-0317 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.38 Ų falls within the moderate polarity range, balancing permeability and solubility for 8R-0317. Following Lipinski's Rule of Five, 8R-0317 has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8R-0317?

The CAS number of 8R-0317 is 1024618-15-2.

What is the molecular formula of 8R-0317?

The molecular formula of 8R-0317 is C19H19ClN4O3S2.

What is the molecular weight of 8R-0317?

The molecular weight of 8R-0317 is 450.06 g/mol.

Where can I buy 8R-0317?

You can request a quote for 8R-0317 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8R-0317?

Yes, KEHONG BIO provides custom synthesis services for 8R-0317 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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