格列本脲
TL;DR: 格列本脲 (CAS 10238-21-8) is a chemical compound with molecular formula C23H28ClN3O5S and molecular weight 493.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
格列本脲
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
Also Known As: Glibenclamide, glyburide, Glybenclamide, Glynase, Micronase
| Molecular Formula | C23H28ClN3O5S |
|---|---|
| Molecular Weight | 493.14 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 122.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 493.14383 |
| Heavy Atoms | 33 |
| Complexity | 746.0 |
| Melting Point | 169 |
| Solubility | 2.06e-03 g/L |
Chemical Identifiers
| CAS Number | 10238-21-8 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3 |
| InChIKey | ZNNLBTZKUZBEKO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 19 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
格列本脲 (CAS 10238-21-8), with molecular formula C23H28ClN3O5S and molecular weight 493.14 g/mol. IUPAC: 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide.
Chemical Property Profile of 格列本脲
Property Insights of 格列本脲
The XLogP value of 4.8 indicates that 格列苯脲 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 格列本脲. Following Lipinski's Rule of Five, 格列苯脲 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 格列苯脲?
The CAS number of 格列苯脲 is 10238-21-8.
What is the molecular formula of 格列苯脲?
The molecular formula of 格列苯脲 is C23H28ClN3O5S.
What is the molecular weight of 格列苯脲?
The molecular weight of 格列苯脲 is 493.14 g/mol.
Where can I buy 格列苯脲?
You can request a quote for 格列苯脲 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 格列苯脲?
Yes, KEHONG BIO provides custom synthesis services for 格列苯脲 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.