COX-2-IN-43
TL;DR: COX-2-IN-43 (CAS 1023524-40-4) is a chemical compound with molecular formula C18H11Cl2F3N2O3 and molecular weight 430.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(2,6-dichlorophenyl)-5-methyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxamide
Also Known As: COX-2-IN-43, 3-(2,6-dichlorophenyl)-5-methyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxamide, (3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL)-N-(4-(TRIFLUOROMETHOXY)PHENYL)FORMAMIDE, 3-(2,6-dichlorophenyl)-5-methyl-N-[4-(trifluoromethoxy)phenyl]isoxazole-4-carboxamide, C18H11Cl2F3N2O3
| Molecular Formula | C18H11Cl2F3N2O3 |
|---|---|
| Molecular Weight | 430.01 g/mol |
| LogP | 6.10772 |
| Topological Polar Surface Area | 64.36 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 430.0099 |
| Heavy Atoms | 28 |
| Complexity | 997.6556 |
Chemical Identifiers
| CAS Number | 1023524-40-4 |
|---|---|
| SMILES | CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)NC3=CC=C(C=C3)OC(F)(F)F |
Product Overview
COX-2-IN-43 (CAS 1023524-40-4), with molecular formula C18H11Cl2F3N2O3 and molecular weight 430.01 g/mol. IUPAC: 3-(2,6-dichlorophenyl)-5-methyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxamide.
Chemical Property Profile of COX-2-IN-43
Property Insights of COX-2-IN-43
The XLogP value of 6.10772 indicates that COX-2-IN-43 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.36 Ų falls within the moderate polarity range, balancing permeability and solubility for COX-2-IN-43. Following Lipinski's Rule of Five, COX-2-IN-43 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of COX-2-IN-43?
The CAS number of COX-2-IN-43 is 1023524-40-4.
What is the molecular formula of COX-2-IN-43?
The molecular formula of COX-2-IN-43 is C18H11Cl2F3N2O3.
What is the molecular weight of COX-2-IN-43?
The molecular weight of COX-2-IN-43 is 430.01 g/mol.
Where can I buy COX-2-IN-43?
You can request a quote for COX-2-IN-43 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for COX-2-IN-43?
Yes, KEHONG BIO provides custom synthesis services for COX-2-IN-43 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.