VU0496843-1
TL;DR: VU0496843-1 (CAS 1021060-76-3) is a chemical compound with molecular formula C22H18ClFN4O and molecular weight 408.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-1-(4-fluorophenyl)-3-methyl-N-(2-phenylethyl)pyrazolo[3,4-b]pyridine-5-carboxamide
Also Known As: VU0496843-1, F2759-0360, 4-chloro-1-(4-fluorophenyl)-3-methyl-N-phenethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, 4-chloro-1-(4-fluorophenyl)-3-methyl-N-(2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, 4-chloro-1-(4-fluorophenyl)-3-methyl-N-(2-phenylethyl)pyrazolo[3,4-b]pyridine-5-carboxamide
| Molecular Formula | C22H18ClFN4O |
|---|---|
| Molecular Weight | 408.12 g/mol |
| LogP | 4.49392 |
| Topological Polar Surface Area | 59.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 408.11533 |
| Heavy Atoms | 29 |
| Complexity | 1173.1194 |
Chemical Identifiers
| CAS Number | 1021060-76-3 |
|---|---|
| SMILES | CC1=NN(C2=NC=C(C(=C12)Cl)C(=O)NCCC3=CC=CC=C3)C4=CC=C(C=C4)F |
Product Overview
VU0496843-1 (CAS 1021060-76-3), with molecular formula C22H18ClFN4O and molecular weight 408.12 g/mol. IUPAC: 4-chloro-1-(4-fluorophenyl)-3-methyl-N-(2-phenylethyl)pyrazolo[3,4-b]pyridine-5-carboxamide.
Chemical Property Profile of VU0496843-1
Property Insights of VU0496843-1
The XLogP value of 4.49392 indicates that VU0496843-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.81 Ų, VU0496843-1 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, VU0496843-1 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of VU0496843-1?
The CAS number of VU0496843-1 is 1021060-76-3.
What is the molecular formula of VU0496843-1?
The molecular formula of VU0496843-1 is C22H18ClFN4O.
What is the molecular weight of VU0496843-1?
The molecular weight of VU0496843-1 is 408.12 g/mol.
Where can I buy VU0496843-1?
You can request a quote for VU0496843-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for VU0496843-1?
Yes, KEHONG BIO provides custom synthesis services for VU0496843-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.