VU0496841-1
TL;DR: VU0496841-1 (CAS 1021025-11-5) is a chemical compound with molecular formula C19H14ClFN4OS and molecular weight 400.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-1-(4-fluorophenyl)-3-methyl-N-(thiophen-2-ylmethyl)pyrazolo[3,4-b]pyridine-5-carboxamide
Also Known As: VU0496841-1, F2759-0283, 4-chloro-1-(4-fluorophenyl)-3-methyl-N-(thiophen-2-ylmethyl)pyrazolo[3,4-b]pyridine-5-carboxamide, 4-chloro-1-(4-fluorophenyl)-3-methyl-N-[(thiophen-2-yl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, 4-chloro-1-(4-fluorophenyl)-3-methyl-N-(thiophen-2-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
| Molecular Formula | C19H14ClFN4OS |
|---|---|
| Molecular Weight | 400.06 g/mol |
| LogP | 4.51292 |
| Topological Polar Surface Area | 59.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 400.0561 |
| Heavy Atoms | 27 |
| Complexity | 1123.0359 |
Chemical Identifiers
| CAS Number | 1021025-11-5 |
|---|---|
| SMILES | CC1=NN(C2=NC=C(C(=C12)Cl)C(=O)NCC3=CC=CS3)C4=CC=C(C=C4)F |
Product Overview
VU0496841-1 (CAS 1021025-11-5), with molecular formula C19H14ClFN4OS and molecular weight 400.06 g/mol. IUPAC: 4-chloro-1-(4-fluorophenyl)-3-methyl-N-(thiophen-2-ylmethyl)pyrazolo[3,4-b]pyridine-5-carboxamide.
Chemical Property Profile of VU0496841-1
Property Insights of VU0496841-1
The XLogP value of 4.51292 indicates that VU0496841-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.81 Ų, VU0496841-1 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, VU0496841-1 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of VU0496841-1?
The CAS number of VU0496841-1 is 1021025-11-5.
What is the molecular formula of VU0496841-1?
The molecular formula of VU0496841-1 is C19H14ClFN4OS.
What is the molecular weight of VU0496841-1?
The molecular weight of VU0496841-1 is 400.06 g/mol.
Where can I buy VU0496841-1?
You can request a quote for VU0496841-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for VU0496841-1?
Yes, KEHONG BIO provides custom synthesis services for VU0496841-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.