Zardaverine
TL;DR: Zardaverine (CAS 101975-10-4) is a chemical compound with molecular formula C12H10F2N2O3 and molecular weight 268.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one
Also Known As: zardaverine, Zardaverina, Zardaverinum, Zardaverine [INN], Zaradaverine
| Molecular Formula | C12H10F2N2O3 |
|---|---|
| Molecular Weight | 268.07 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 59.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 268.06595 |
| Heavy Atoms | 19 |
| Complexity | 398.0 |
Chemical Identifiers
| CAS Number | 101975-10-4 |
|---|---|
| SMILES | COC1=C(C=CC(=C1)C2=NNC(=O)C=C2)OC(F)F |
| InChIKey | HJMQDJPMQIHLPB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Zardaverine (CAS 101975-10-4), with molecular formula C12H10F2N2O3 and molecular weight 268.07 g/mol. IUPAC: 3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one.
Chemical Property Profile of Zardaverine
Property Insights of Zardaverine
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Zardaverine. With a topological polar surface area (TPSA) of 59.9 Ų, Zardaverine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Zardaverine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Zardaverine?
The CAS number of Zardaverine is 101975-10-4.
What is the molecular formula of Zardaverine?
The molecular formula of Zardaverine is C12H10F2N2O3.
What is the molecular weight of Zardaverine?
The molecular weight of Zardaverine is 268.07 g/mol.
Where can I buy Zardaverine?
You can request a quote for Zardaverine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Zardaverine?
Yes, KEHONG BIO provides custom synthesis services for Zardaverine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.