N-Boc-trans-4-N-Fmoc-amino-L-proline
TL;DR: N-Boc-trans-4-N-Fmoc-amino-L-proline (CAS 1018332-23-4) is a chemical compound with molecular formula C25H28N2O6 and molecular weight 452.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,4R)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
Also Known As: N-Boc-trans-4-N-Fmoc-amino-L-proline, (2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid, fmoc-abpc(2s,4r)-oh, Boc-L-Pro(4-NHFmoc)-OH, Boc-trans-4-N-Fmoc-Pro-OH
| Molecular Formula | C25H28N2O6 |
|---|---|
| Molecular Weight | 452.19 g/mol |
| LogP | 3.9877 |
| Topological Polar Surface Area | 105.17 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 452.19473 |
| Heavy Atoms | 33 |
| Complexity | 1031.062 |
Chemical Identifiers
| CAS Number | 1018332-23-4 |
|---|---|
| SMILES | CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24 |
Product Overview
N-Boc-trans-4-N-Fmoc-amino-L-proline (CAS 1018332-23-4), with molecular formula C25H28N2O6 and molecular weight 452.19 g/mol. IUPAC: (2S,4R)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid.
Chemical Property Profile of N-Boc-trans-4-N-Fmoc-amino-L-proline
Property Insights of N-Boc-trans-4-N-Fmoc-amino-L-proline
The XLogP value of 3.9877 indicates that N-Boc-trans-4-N-Fmoc-amino-L-proline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 105.17 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Boc-trans-4-N-Fmoc-amino-L-proline. Following Lipinski's Rule of Five, N-Boc-trans-4-N-Fmoc-amino-L-proline has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Boc-trans-4-N-Fmoc-amino-L-proline?
The CAS number of N-Boc-trans-4-N-Fmoc-amino-L-proline is 1018332-23-4.
What is the molecular formula of N-Boc-trans-4-N-Fmoc-amino-L-proline?
The molecular formula of N-Boc-trans-4-N-Fmoc-amino-L-proline is C25H28N2O6.
What is the molecular weight of N-Boc-trans-4-N-Fmoc-amino-L-proline?
The molecular weight of N-Boc-trans-4-N-Fmoc-amino-L-proline is 452.19 g/mol.
Where can I buy N-Boc-trans-4-N-Fmoc-amino-L-proline?
You can request a quote for N-Boc-trans-4-N-Fmoc-amino-L-proline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Boc-trans-4-N-Fmoc-amino-L-proline?
Yes, KEHONG BIO provides custom synthesis services for N-Boc-trans-4-N-Fmoc-amino-L-proline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.