![1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one structure](/static/products/101/1017526-77-0.png)
1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one
TL;DR: 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one (CAS 1017526-77-0) is a chemical compound with molecular formula C25H27N5O3 and molecular weight 445.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-1-[3-(dimethylamino)propyl]-4-[hydroxy-(5-methyl-1-phenylpyrazol-4-yl)methylidene]-5-pyridin-2-ylpyrrolidine-2,3-dione
Also Known As: 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one, (4E)-1-[3-(dimethylamino)propyl]-4-[hydroxy-(5-methyl-1-phenylpyrazol-4-yl)methylidene]-5-pyridin-2-ylpyrrolidine-2,3-dione, 1-[3-(dimethylamino)propyl]-3-hydroxy-4-[(5-methyl-1-phenyl-1H-pyrazol-4-yl)carbonyl]-5-(2-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one, 1-[3-(dimethylamino)propyl]-3-hydroxy-4-[(5-methyl-1-phenylpyrazol-4-yl)carbon yl]-5-(2-pyridyl)-3-pyrrolin-2-one
| Molecular Formula | C25H27N5O3 |
|---|---|
| Molecular Weight | 445.21 g/mol |
| LogP | 2.94912 |
| Topological Polar Surface Area | 91.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 445.2114 |
| Heavy Atoms | 33 |
| Complexity | 1185.2661 |
Chemical Identifiers
| CAS Number | 1017526-77-0 |
|---|---|
| SMILES | CC1=C(C=NN1C2=CC=CC=C2)/C(=C\3/C(N(C(=O)C3=O)CCCN(C)C)C4=CC=CC=N4)/O |
Product Overview
1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one (CAS 1017526-77-0), with molecular formula C25H27N5O3 and molecular weight 445.21 g/mol. IUPAC: (4E)-1-[3-(dimethylamino)propyl]-4-[hydroxy-(5-methyl-1-phenylpyrazol-4-yl)methylidene]-5-pyridin-2-ylpyrrolidine-2,3-dione.
Chemical Property Profile of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one
Property Insights of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one
The XLogP value of 2.94912 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one. The TPSA of 91.56 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one. Following Lipinski's Rule of Five, 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
The CAS number of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one is 1017526-77-0.
What is the molecular formula of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
The molecular formula of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one is C25H27N5O3.
What is the molecular weight of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
The molecular weight of 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one is 445.21 g/mol.
Where can I buy 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
You can request a quote for 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-(dimethylamino)propyl]-3-hydroxy-4-(5-methyl-1-phenyl-1H-pyrazole-4-carbonyl)-5-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.