NCI60_022775 structure

NCI60_022775

TL;DR: NCI60_022775 (CAS 101725-90-0) is a chemical compound with molecular formula C20H26FN3O3 and molecular weight 375.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(dimethylamino)-8-[4-(4-fluorophenyl)-4-oxobutyl]-2,8-diazaspiro[4.5]decane-1,3-dione

Also Known As: NCI60_022775, 2,8-Diazaspiro(4.5)decane-1,3-dione, 2-(dimethylamino)-8-(3-(p-fluorobenzoyl)propyl)-, 2-Dimethylamino-8-(3-p-fluorobenzoylpropyl)-2,8-diazaspiro(4.5)decane-1,3-dione, 2-(Dimethylamino)-8-(4-(4-fluorophenyl)-4-oxobutyl)-2,8-diazaspiro[4.5]decane-1,3-dione, 2-(dimethylamino)-8-[4-(4-fluorophenyl)-4-oxobutyl]-2,8-diazaspiro[4.5]decane-1,3-dione

CAS: 101725-90-0
Molecular Formula C20H26FN3O3
Molecular Weight 375.20 g/mol
LogP 1.5
Topological Polar Surface Area 60.9 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 375.19583
Heavy Atoms 27
Complexity 579.0

Chemical Identifiers

CAS Number 101725-90-0
SMILES CN(C)N1C(=O)CC2(C1=O)CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F
InChIKey ILVXNXRHHAUIEM-UHFFFAOYSA-N

Product Overview

NCI60_022775 (CAS 101725-90-0), with molecular formula C20H26FN3O3 and molecular weight 375.20 g/mol. IUPAC: 2-(dimethylamino)-8-[4-(4-fluorophenyl)-4-oxobutyl]-2,8-diazaspiro[4.5]decane-1,3-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NCI60_022775

XLogP
1.5
TPSA (Topological Polar Surface Area)
60.9
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
27
Complexity
579.0
Exact Mass
375.19583
Monoisotopic Mass
375.19583
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NCI60_022775

The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for NCI60_022775. The TPSA of 60.9 Ų falls within the moderate polarity range, balancing permeability and solubility for NCI60_022775. Following Lipinski's Rule of Five, NCI60_022775 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NCI60_022775?

The CAS number of NCI60_022775 is 101725-90-0.

What is the molecular formula of NCI60_022775?

The molecular formula of NCI60_022775 is C20H26FN3O3.

What is the molecular weight of NCI60_022775?

The molecular weight of NCI60_022775 is 375.20 g/mol.

Where can I buy NCI60_022775?

You can request a quote for NCI60_022775 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NCI60_022775?

Yes, KEHONG BIO provides custom synthesis services for NCI60_022775 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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