Pentamethylphosphoramide structure

Pentamethylphosphoramide

TL;DR: Pentamethylphosphoramide (CAS 10159-46-3) is a chemical compound with molecular formula C5H16N3OP and molecular weight 165.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[bis(dimethylamino)phosphoryl]methanamine

Also Known As: Pentamethylphosphoramide, Pentamethylphosphoric triamide, pentamethyl-phosphamide, Phosphoric triamide, pentamethyl-, N-[bis(dimethylamino)phosphoryl]methanamine

CAS: 10159-46-3
Molecular Formula C5H16N3OP
Molecular Weight 165.10 g/mol
LogP -0.4
Topological Polar Surface Area 35.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 165.1031
Heavy Atoms 10
Complexity 134.0

Chemical Identifiers

CAS Number 10159-46-3
SMILES CNP(=O)(N(C)C)N(C)C
InChIKey JSJBYUNWLNWERF-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.

Biotechnology (5 patents) Heterocyclic Building Blocks (1 patents) Organic Building Blocks (9 patents) Organometallic Reagents (3 patents) Plastic Additives (5 patents) +2 more

Product Overview

Pentamethylphosphoramide (CAS 10159-46-3), with molecular formula C5H16N3OP and molecular weight 165.10 g/mol. IUPAC: N-[bis(dimethylamino)phosphoryl]methanamine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pentamethylphosphoramide

XLogP
-0.4
TPSA (Topological Polar Surface Area)
35.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
10
Complexity
134.0
Exact Mass
165.1031
Monoisotopic Mass
165.1031
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pentamethylphosphoramide

The XLogP value of -0.4 indicates that Pentamethylphosphoramide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 35.6 Ų, Pentamethylphosphoramide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pentamethylphosphoramide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pentamethylphosphoramide?

The CAS number of Pentamethylphosphoramide is 10159-46-3.

What is the molecular formula of Pentamethylphosphoramide?

The molecular formula of Pentamethylphosphoramide is C5H16N3OP.

What is the molecular weight of Pentamethylphosphoramide?

The molecular weight of Pentamethylphosphoramide is 165.10 g/mol.

Where can I buy Pentamethylphosphoramide?

You can request a quote for Pentamethylphosphoramide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pentamethylphosphoramide?

Yes, KEHONG BIO provides custom synthesis services for Pentamethylphosphoramide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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