![2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide structure](/static/products/1015/1015856-33-3.webp)
2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide
TL;DR: 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide (CAS 1015856-33-3) is a chemical compound with molecular formula C17H13ClF3N5O3S and molecular weight 459.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N'-(2-chloroacetyl)-2-[3-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carbohydrazide
Also Known As: 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide, N'-(2-chloroacetyl)-2-[3-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carbohydrazide, N'-(chloroacetyl)-2-[3-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carbohydrazide
| Molecular Formula | C17H13ClF3N5O3S |
|---|---|
| Molecular Weight | 459.04 g/mol |
| LogP | 3.023 |
| Topological Polar Surface Area | 98.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 459.03796 |
| Heavy Atoms | 30 |
| Complexity | 1065.5259 |
Chemical Identifiers
| CAS Number | 1015856-33-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NN(C(=C2)C(F)(F)F)C3=NC(=CS3)C(=O)NNC(=O)CCl |
Product Overview
2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide (CAS 1015856-33-3), with molecular formula C17H13ClF3N5O3S and molecular weight 459.04 g/mol. IUPAC: N'-(2-chloroacetyl)-2-[3-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carbohydrazide.
Chemical Property Profile of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide
Property Insights of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide
The XLogP value of 3.023 indicates that 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 98.14 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide. Following Lipinski's Rule of Five, 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide?
The CAS number of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide is 1015856-33-3.
What is the molecular formula of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide?
The molecular formula of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide is C17H13ClF3N5O3S.
What is the molecular weight of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide?
The molecular weight of 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide is 459.04 g/mol.
Where can I buy 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide?
You can request a quote for 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide?
Yes, KEHONG BIO provides custom synthesis services for 2-[3-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-(2-chloroacetyl)hydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.