![2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide structure](/static/products/1015/1015855-84-1.webp)
2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide
TL;DR: 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide (CAS 1015855-84-1) is a chemical compound with molecular formula C26H18F3N5OS and molecular weight 505.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(3-methylphenyl)methylideneamino]-2-[5-naphthalen-2-yl-3-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxamide
Also Known As: 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide, N-[(3-methylphenyl)methylideneamino]-2-[5-naphthalen-2-yl-3-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxamide
| Molecular Formula | C26H18F3N5OS |
|---|---|
| Molecular Weight | 505.12 g/mol |
| LogP | 6.24012 |
| Topological Polar Surface Area | 72.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 505.1184 |
| Heavy Atoms | 36 |
| Complexity | 1602.743 |
Chemical Identifiers
| CAS Number | 1015855-84-1 |
|---|---|
| SMILES | CC1=CC(=CC=C1)C=NNC(=O)C2=CSC(=N2)N3C(=CC(=N3)C(F)(F)F)C4=CC5=CC=CC=C5C=C4 |
Product Overview
2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide (CAS 1015855-84-1), with molecular formula C26H18F3N5OS and molecular weight 505.12 g/mol. IUPAC: N-[(3-methylphenyl)methylideneamino]-2-[5-naphthalen-2-yl-3-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxamide.
Chemical Property Profile of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide
Property Insights of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide
The XLogP value of 6.24012 indicates that 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.17 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide. Following Lipinski's Rule of Five, 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide?
The CAS number of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide is 1015855-84-1.
What is the molecular formula of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide?
The molecular formula of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide is C26H18F3N5OS.
What is the molecular weight of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide?
The molecular weight of 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide is 505.12 g/mol.
Where can I buy 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide?
You can request a quote for 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide?
Yes, KEHONG BIO provides custom synthesis services for 2-[5-(2-Naphthalenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-4-thiazolecarboxylic acid 2-[(3-methylphenyl)methylene]hydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.