alpha-Monofluorothymidine
TL;DR: alpha-Monofluorothymidine (CAS 101527-45-1) is a chemical compound with molecular formula C10H13FN2O5 and molecular weight 260.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(fluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: alpha-Fluorothymidine, alpha-Monofluorothymidine, F-TDR, Thymidine,, A-fluoro-
| Molecular Formula | C10H13FN2O5 |
|---|---|
| Molecular Weight | 260.08 g/mol |
| LogP | -1.4 |
| Topological Polar Surface Area | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 260.08084 |
| Heavy Atoms | 18 |
| Complexity | 400.0 |
Chemical Identifiers
| CAS Number | 101527-45-1 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)CF)CO)O |
| InChIKey | BQLWSXSBUAEINE-XLPZGREQSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
alpha-Monofluorothymidine (CAS 101527-45-1), with molecular formula C10H13FN2O5 and molecular weight 260.08 g/mol. IUPAC: 5-(fluoromethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of alpha-Monofluorothymidine
Property Insights of alpha-Monofluorothymidine
The XLogP value of -1.4 indicates that alpha-Monofluorothymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for alpha-Monofluorothymidine. Following Lipinski's Rule of Five, alpha-Monofluorothymidine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of alpha-Monofluorothymidine?
The CAS number of alpha-Monofluorothymidine is 101527-45-1.
What is the molecular formula of alpha-Monofluorothymidine?
The molecular formula of alpha-Monofluorothymidine is C10H13FN2O5.
What is the molecular weight of alpha-Monofluorothymidine?
The molecular weight of alpha-Monofluorothymidine is 260.08 g/mol.
Where can I buy alpha-Monofluorothymidine?
You can request a quote for alpha-Monofluorothymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for alpha-Monofluorothymidine?
Yes, KEHONG BIO provides custom synthesis services for alpha-Monofluorothymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.