2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide
TL;DR: 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide (CAS 101512-15-6) is a chemical compound with molecular formula C23H22ClF3N4O and molecular weight 462.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-phenylpiperazin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide;hydrochloride
Also Known As: 2-Morpholin-4-yl-nicotinamide, 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide
| Molecular Formula | C23H22ClF3N4O |
|---|---|
| Molecular Weight | 462.14 g/mol |
| LogP | 5.1011 |
| Topological Polar Surface Area | 48.47 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 462.14343 |
| Heavy Atoms | 32 |
| Complexity | 1054.362 |
Chemical Identifiers
| CAS Number | 101512-15-6 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C3=C(C=CC=N3)C(=O)NC4=CC=CC(=C4)C(F)(F)F.Cl |
Product Overview
2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide (CAS 101512-15-6), with molecular formula C23H22ClF3N4O and molecular weight 462.14 g/mol. IUPAC: 2-(4-phenylpiperazin-1-yl)-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide;hydrochloride.
Chemical Property Profile of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide
Property Insights of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide
The XLogP value of 5.1011 indicates that 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.47 Ų, 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide?
The CAS number of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide is 101512-15-6.
What is the molecular formula of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide?
The molecular formula of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide is C23H22ClF3N4O.
What is the molecular weight of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide?
The molecular weight of 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide is 462.14 g/mol.
Where can I buy 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide?
You can request a quote for 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-Phenyl-piperazin-1-yl)-N-(3-trifluoromethyl-phenyl)-nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.