BUPRENORPHINE B-D-GLUCURONIDE structure

BUPRENORPHINE B-D-GLUCURONIDE

TL;DR: BUPRENORPHINE B-D-GLUCURONIDE (CAS 101224-22-0) is a chemical compound with molecular formula C35H49NO10 and molecular weight 643.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S,3S,4S,5R,6S)-6-[[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-10-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

Also Known As: BUPRENORPHINE B-D-GLUCURONIDE, 17-(Cyclopropylmethyl)-7-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-2-yl hexopyranosiduronic acid, 17-(Cyclopropylmethyl)-7-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-6-methoxy-5alpha,7alpha-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-2-yl beta-D-glucopyranosiduronic acid

CAS: 101224-22-0
Molecular Formula C35H49NO10
Molecular Weight 643.34 g/mol
LogP 1.1
Topological Polar Surface Area 158.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 11
Rotatable Bonds 8
Exact Mass 643.33563
Heavy Atoms 46
Complexity 1240.0

Chemical Identifiers

CAS Number 101224-22-0
SMILES C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=CC(=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)O4)CC8CC8)OC)(C(C)(C)C)O
InChIKey KOTUOCWBKOXDKA-KMMOLZCDSA-N

Product Overview

BUPRENORPHINE B-D-GLUCURONIDE (CAS 101224-22-0), with molecular formula C35H49NO10 and molecular weight 643.34 g/mol. IUPAC: (2S,3S,4S,5R,6S)-6-[[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-10-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of BUPRENORPHINE B-D-GLUCURONIDE

XLogP
1.1
TPSA (Topological Polar Surface Area)
158.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
11
Rotatable Bonds
8
Heavy Atoms
46
Complexity
1240.0
Exact Mass
643.33563
Monoisotopic Mass
643.33563
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of BUPRENORPHINE B-D-GLUCURONIDE

The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for BUPRENORPHINE B-D-GLUCURONIDE. The TPSA of 158.0 Ų indicates high polarity, suggesting BUPRENORPHINE B-D-GLUCURONIDE may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, BUPRENORPHINE B-D-GLUCURONIDE has 5 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of BUPRENORPHINE B-D-GLUCURONIDE?

The CAS number of BUPRENORPHINE B-D-GLUCURONIDE is 101224-22-0.

What is the molecular formula of BUPRENORPHINE B-D-GLUCURONIDE?

The molecular formula of BUPRENORPHINE B-D-GLUCURONIDE is C35H49NO10.

What is the molecular weight of BUPRENORPHINE B-D-GLUCURONIDE?

The molecular weight of BUPRENORPHINE B-D-GLUCURONIDE is 643.34 g/mol.

Where can I buy BUPRENORPHINE B-D-GLUCURONIDE?

You can request a quote for BUPRENORPHINE B-D-GLUCURONIDE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for BUPRENORPHINE B-D-GLUCURONIDE?

Yes, KEHONG BIO provides custom synthesis services for BUPRENORPHINE B-D-GLUCURONIDE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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