![(5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one structure](/static/products/101/1010867-42-1.png)
(5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one
TL;DR: (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one (CAS 1010867-42-1) is a chemical compound with molecular formula C27H23N5OS and molecular weight 465.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one
Also Known As: (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one, (5Z)-2-[4-(naphthalen-1-yl)piperazin-1-yl]-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4(5H)-one, (Z)-2-(4-(naphthalen-1-yl)piperazin-1-yl)-5-((3-phenyl-1H-pyrazol-4-yl)methylene)thiazol-4(5H)-one, 2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(3-phenyl-2H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one
| Molecular Formula | C27H23N5OS |
|---|---|
| Molecular Weight | 465.16 g/mol |
| LogP | 5.0224 |
| Topological Polar Surface Area | 64.59 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 465.16232 |
| Heavy Atoms | 34 |
| Complexity | 1412.0067 |
Chemical Identifiers
| CAS Number | 1010867-42-1 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC3=CC=CC=C32)C4=NC(=O)/C(=C/C5=C(NN=C5)C6=CC=CC=C6)/S4 |
Product Overview
(5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one (CAS 1010867-42-1), with molecular formula C27H23N5OS and molecular weight 465.16 g/mol. IUPAC: (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one
Property Insights of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one
The XLogP value of 5.0224 indicates that (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.59 Ų falls within the moderate polarity range, balancing permeability and solubility for (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one. Following Lipinski's Rule of Five, (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one?
The CAS number of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one is 1010867-42-1.
What is the molecular formula of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one?
The molecular formula of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one is C27H23N5OS.
What is the molecular weight of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one?
The molecular weight of (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one is 465.16 g/mol.
Where can I buy (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one?
You can request a quote for (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-2-(4-naphthalen-1-ylpiperazin-1-yl)-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-thiazol-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.