KCNQ1 activator-1
TL;DR: KCNQ1 activator-1 (CAS 1008671-38-2) is a chemical compound with molecular formula C22H23N3O4S2 and molecular weight 457.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine-2-carboxamide
Also Known As: KCNQ1 activator-1, KCNQ1 activator-1?, N-(4-(4-Methoxyphenyl)thiazol-2-yl)-1-(phenylsulfonyl)piperidine-2-carboxamide, SDCCGSBI-0661705.P001, 1-(benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine-2-carboxamide
| Molecular Formula | C22H23N3O4S2 |
|---|---|
| Molecular Weight | 457.11 g/mol |
| LogP | 4.0006 |
| Topological Polar Surface Area | 88.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 457.113 |
| Heavy Atoms | 31 |
| Complexity | 1145.0138 |
Chemical Identifiers
| CAS Number | 1008671-38-2 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3CCCCN3S(=O)(=O)C4=CC=CC=C4 |
Product Overview
KCNQ1 activator-1 (CAS 1008671-38-2), with molecular formula C22H23N3O4S2 and molecular weight 457.11 g/mol. IUPAC: 1-(benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine-2-carboxamide.
Chemical Property Profile of KCNQ1 activator-1
Property Insights of KCNQ1 activator-1
The XLogP value of 4.0006 indicates that KCNQ1 activator-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.6 Ų falls within the moderate polarity range, balancing permeability and solubility for KCNQ1 activator-1. Following Lipinski's Rule of Five, KCNQ1 activator-1 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of KCNQ1 activator-1?
The CAS number of KCNQ1 activator-1 is 1008671-38-2.
What is the molecular formula of KCNQ1 activator-1?
The molecular formula of KCNQ1 activator-1 is C22H23N3O4S2.
What is the molecular weight of KCNQ1 activator-1?
The molecular weight of KCNQ1 activator-1 is 457.11 g/mol.
Where can I buy KCNQ1 activator-1?
You can request a quote for KCNQ1 activator-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for KCNQ1 activator-1?
Yes, KEHONG BIO provides custom synthesis services for KCNQ1 activator-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.