![4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one structure](/static/products/100/10074-06-3.png)
4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one
TL;DR: 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one (CAS 10074-06-3) is a chemical compound with molecular formula C16H14N2OS and molecular weight 282.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-thiophen-2-yl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one
Also Known As: J3.281.936B, 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one, 4-thiophen-2-yl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one, 4-<2>Thienyl-3,4,5,6-tetrahydro-benzo
| Molecular Formula | C16H14N2OS |
|---|---|
| Molecular Weight | 282.08 g/mol |
| LogP | 3.4595 |
| Topological Polar Surface Area | 41.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 282.08267 |
| Heavy Atoms | 20 |
| Complexity | 703.0268 |
Chemical Identifiers
| CAS Number | 10074-06-3 |
|---|---|
| SMILES | C1CC2=C(C3=CC=CC=C31)NC(=O)NC2C4=CC=CS4 |
Product Overview
4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one (CAS 10074-06-3), with molecular formula C16H14N2OS and molecular weight 282.08 g/mol. IUPAC: 4-thiophen-2-yl-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one.
Chemical Property Profile of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one
Property Insights of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one
The XLogP value of 3.4595 indicates that 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.13 Ų, 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one?
The CAS number of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one is 10074-06-3.
What is the molecular formula of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one?
The molecular formula of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one is C16H14N2OS.
What is the molecular weight of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one?
The molecular weight of 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one is 282.08 g/mol.
Where can I buy 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one?
You can request a quote for 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(thiophen-2-yl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.