![[5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone structure](/static/products/1005/1005638-50-5.webp)
[5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone
TL;DR: [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone (CAS 1005638-50-5) is a chemical compound with molecular formula C22H19F3N6O and molecular weight 440.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[5-(1,3-dimethylpyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2-methyl-2,3-dihydroindol-1-yl)methanone
Also Known As: [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone|[5-(1,3-dimethylpyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2-methyl-2,3-dihydroindol-1-yl)methanone
| Molecular Formula | C22H19F3N6O |
|---|---|
| Molecular Weight | 440.16 g/mol |
| LogP | 4.04842 |
| Topological Polar Surface Area | 68.32 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 440.15726 |
| Heavy Atoms | 32 |
| Complexity | 1369.999 |
Chemical Identifiers
| CAS Number | 1005638-50-5 |
|---|---|
| SMILES | CC1CC2=CC=CC=C2N1C(=O)C3=NN4C(=CC(=NC4=C3)C5=CN(N=C5C)C)C(F)(F)F |
Product Overview
[5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone (CAS 1005638-50-5), with molecular formula C22H19F3N6O and molecular weight 440.16 g/mol. IUPAC: [5-(1,3-dimethylpyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2-methyl-2,3-dihydroindol-1-yl)methanone.
Chemical Property Profile of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone
Property Insights of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone
The XLogP value of 4.04842 indicates that [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.32 Ų falls within the moderate polarity range, balancing permeability and solubility for [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone. Following Lipinski's Rule of Five, [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone?
The CAS number of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone is 1005638-50-5.
What is the molecular formula of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone?
The molecular formula of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone is C22H19F3N6O.
What is the molecular weight of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone?
The molecular weight of [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone is 440.16 g/mol.
Where can I buy [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone?
You can request a quote for [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for [5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl](2-methyl-2,3-dihydro-1H-indol-1-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.