![5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/1005/1005589-21-8.webp)
5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
TL;DR: 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 1005589-21-8) is a chemical compound with molecular formula C19H15F4N7O3 and molecular weight 465.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide, 5,7-bis(difluoromethyl)-N-{5-[(furan-2-ylmethyl)carbamoyl]-1-methyl-1H-pyrazol-4-yl}pyrazolo[1,5-a]pyrimidine-2-carboxamide, 5,7-BIS(DIFLUOROMETHYL)-N~2~-(5-{[(2-FURYLMETHYL)AMINO]CARBONYL}-1-METHYL-1H-PYRAZOL-4-YL)PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXAMIDE
| Molecular Formula | C19H15F4N7O3 |
|---|---|
| Molecular Weight | 465.12 g/mol |
| LogP | 3.1133 |
| Topological Polar Surface Area | 119.35 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 465.11725 |
| Heavy Atoms | 33 |
| Complexity | 1314.6431 |
Chemical Identifiers
| CAS Number | 1005589-21-8 |
|---|---|
| SMILES | CN1C(=C(C=N1)NC(=O)C2=NN3C(=CC(=NC3=C2)C(F)F)C(F)F)C(=O)NCC4=CC=CO4 |
Product Overview
5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 1005589-21-8), with molecular formula C19H15F4N7O3 and molecular weight 465.12 g/mol. IUPAC: 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
Property Insights of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
The XLogP value of 3.1133 indicates that 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 119.35 Ų falls within the moderate polarity range, balancing permeability and solubility for 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide. Following Lipinski's Rule of Five, 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The CAS number of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide is 1005589-21-8.
What is the molecular formula of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular formula of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide is C19H15F4N7O3.
What is the molecular weight of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular weight of 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide is 465.12 g/mol.
Where can I buy 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide?
You can request a quote for 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5,7-bis(difluoromethyl)-N-[5-(furan-2-ylmethylcarbamoyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.