AEM2
TL;DR: AEM2 (CAS 1005095-04-4) is a chemical compound with molecular formula C27H27N3O and molecular weight 409.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-phenyl-N-(pyridin-3-ylmethyl)-9-azatetracyclo[10.2.1.02,11.03,8]pentadeca-3(8),4,6-triene-5-carboxamide
Also Known As: AEM2, AEM2(SIRT2inhibitorAEM2), BAS 06741394, J3.735.430I, AH-487/42142897
| Molecular Formula | C27H27N3O |
|---|---|
| Molecular Weight | 409.22 g/mol |
| LogP | 5.3081 |
| Topological Polar Surface Area | 54.02 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 409.21542 |
| Heavy Atoms | 31 |
| Complexity | 1097.9791 |
Chemical Identifiers
| CAS Number | 1005095-04-4 |
|---|---|
| SMILES | C1CC2CC1C3C2C4=C(C=CC(=C4)C(=O)NCC5=CN=CC=C5)NC3C6=CC=CC=C6 |
Product Overview
AEM2 (CAS 1005095-04-4), with molecular formula C27H27N3O and molecular weight 409.22 g/mol. IUPAC: 10-phenyl-N-(pyridin-3-ylmethyl)-9-azatetracyclo[10.2.1.02,11.03,8]pentadeca-3(8),4,6-triene-5-carboxamide.
Chemical Property Profile of AEM2
Property Insights of AEM2
The XLogP value of 5.3081 indicates that AEM2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.02 Ų, AEM2 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AEM2 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AEM2?
The CAS number of AEM2 is 1005095-04-4.
What is the molecular formula of AEM2?
The molecular formula of AEM2 is C27H27N3O.
What is the molecular weight of AEM2?
The molecular weight of AEM2 is 409.22 g/mol.
Where can I buy AEM2?
You can request a quote for AEM2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AEM2?
Yes, KEHONG BIO provides custom synthesis services for AEM2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.