6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
TL;DR: 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one (CAS 1005090-38-9) is a chemical compound with molecular formula C28H23F3N4O3 and molecular weight 520.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(1,3-diphenylpyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)-1,3-diazinan-2-one
Also Known As: 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one, F1260-1211, 6-(1,3-diphenylpyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)-1,3-diazinan-2-one, 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)-1,3-diazinan-2-one, 4-hydroxy-6-(1-phenyl-3-phenyl-4-pyrazolyl)-5-(p-toluoyl)-4-(trifluoromethyl)tetrahydro-2(1H)-pyrimidinone
| Molecular Formula | C28H23F3N4O3 |
|---|---|
| Molecular Weight | 520.17 g/mol |
| LogP | 4.95162 |
| Topological Polar Surface Area | 96.25 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 520.17224 |
| Heavy Atoms | 38 |
| Complexity | 1470.982 |
Chemical Identifiers
| CAS Number | 1005090-38-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C(=O)C2C(NC(=O)NC2(C(F)(F)F)O)C3=CN(N=C3C4=CC=CC=C4)C5=CC=CC=C5 |
Product Overview
6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one (CAS 1005090-38-9), with molecular formula C28H23F3N4O3 and molecular weight 520.17 g/mol. IUPAC: 6-(1,3-diphenylpyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)-1,3-diazinan-2-one.
Chemical Property Profile of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
Property Insights of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
The XLogP value of 4.95162 indicates that 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.25 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one. Following Lipinski's Rule of Five, 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one?
The CAS number of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one is 1005090-38-9.
What is the molecular formula of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one?
The molecular formula of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one is C28H23F3N4O3.
What is the molecular weight of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one?
The molecular weight of 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one is 520.17 g/mol.
Where can I buy 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one?
You can request a quote for 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-hydroxy-5-(4-methylbenzoyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.